点地梅属植物化学成分与药理活性研究进展  

Phytochemical and Biological Studies on Plants from the Genus Androsace

作　　者：何希瑞[1] 魏桂芳[1] 姚宏[1] 常育[1] 徐磊[1] 张春玲[1] 

机构地区：[1]西安交通大学医学院附属红会医院,西安710054

出　　处：《中国实验方剂学杂志》2012年第11期296-299,共4页Chinese Journal of Experimental Traditional Medical Formulae

摘　　要：主要从化学成分、药理活性及临床应用方面对国内外点地梅属植物研究概况进行整理,希望能够有助于点地梅属药用植物的开发和利用。借助CNKI数据库以题名或关键词为"点地梅",PubMed以及Science Direct数据库系统以题名或关键词为"Androsace"经行检索,整理了近年来有关点地梅属植物的化学成分、药理活性及临床应用研究成果。点地梅属植物是报春花科(Primulaceae)植物中的一个大属。全世界约有100种,医药前景良好。目前,已经从点地梅属药用植物中分离得到30多种化合物,其中黄酮和三萜皂苷类为主要含有成分。体内外实验研究表明,点地梅属药用植物的粗提取物和单体化合物(三萜皂苷类成分)具有广泛的药理作用,尤其是在抗肿瘤、抗早孕和抗病毒方面效果显著。The present paper reviews the chemical compounds,the biological activities and clinical application of Androsace plants,which would provide references for development and utilization of Androsac genus.Index the literatures in CNKI,PubMed and Science Direct direct databases choosing titles or Key words as ＇Androsace＇.Androsace is an important genus of the family Primulaceae.About 100 species distribute in many zones of the world.Up to now,more than 30 compounds have been isolated and identified,and the flavonoids and triterpenoid saponins are the main constitutent.In vivo and in vitro studies indicated that rude extracts and monomer compounds（triterpenoid saponins） from genus Androsace possessed wide pharmacological actions,especially in anti-tumor,anti-early pregnancy and anti-viruses,etc.

关 键 词：点地梅属 黄酮类 三萜皂苷类 抗肿瘤 

分 类 号：R284[医药卫生—中药学] R285[医药卫生—中医学]