嗜麦芽窄食单胞菌感染的研究进展  

Progress in sWnotrophomonas maltophilia

作　　者：东丽丽(综述)[1] 卢美萍(审校)[1] 

机构地区：[1]浙江大学医学院附属儿童医院呼吸科,杭州310003

出　　处：《国际儿科学杂志》2012年第3期230-233,共4页International Journal of Pediatrics

基　　金：国家自然科学基金资助项目（81070012）;浙江省自然科学基金资助项目（Y2090339）

摘　　要：嗜麦芽窄食单胞菌是一种能导致难治性感染，并存在多种目前尚未明确的多重耐药的条件致病浦，尤其在免疫抑制患者中多见。尽管毒力不强，但由于其能在呼吸道上皮细胞和医疗器械表面定植，因此是住院患者的重要致病菌。同时，由于其对多种抗生素如碳青霉烯类天然耐药，以及对一线用药复方新诺明的耐药星升高趋势，目前对嗜麦芽窄食单胞菌感染的治疗受到了较大的挑战。近年来，嗜麦芽窄食单胞菌感染的预防和治疗备受关注。Stenotrophomonas maltophilia （SMA） is a emerging opportunistic pathogen that can cause difficult-to-treat infections and exhibits significant degrees of poorly understood multidrug resistance, especially in immunocompromised patients . SMA is not an inherent virulent pathogen, but it can colonize in respiratorytract epithelial cells and surfaces of medical devices make it an important colonizer in hospitalized patients. Man- agement of SMA infection is hampered because of its high-level intrinsic resistance to many antibiotics and the increasing occurrence of acquired resistance to the first-line drug such as co-trimoxazole. The prevention and treatment of SMA infection attract more and more attention in recent years.

关 键 词：嗜友芽窄食单胞菌 感染 耐药 

分 类 号：R378.99[医药卫生—病原生物学]