幼儿急性早幼粒细胞白血病1例并文献复习  

A case of infant acute promyelocytic leukemia and review of literature

作　　者：徐双年[1] 陈洁平[1] 李庆容[1] 

机构地区：[1]第三军医大学西南医院血液病中心,重庆400038

出　　处：《海南医学》2012年第12期57-59,共3页Hainan Medical Journal

摘　　要：目的探讨幼儿急性早幼粒细胞白血病的临床特点、治疗难点所在,加深对这一亚类的白血病的认识,提高救治效率。方法报道1例经全反式维甲酸治疗缓解的幼儿急性早幼粒细胞白血病病例,并结合文献总结这一类疾病的发病和治疗特点。结果尽管这一亚类的白血病经过常规的诱导缓解方案能够获得满意疗效,但护理难度大、依从性差,会给临床治疗带来较大的障碍。结论幼儿APL采用规范化的治疗可以获得良好的治疗效果,重要的是要增强其对治疗的依从性,鼓励其接受正规方案的治疗,避免转变成为复发难治型。Objective To investigate the clinical characteristics and therapeutical difficulty of infant acute promyelocytie leukemia, and to improve treatment efficacy. Methods We collected and analyzed the clinical data of an infant with acute promyelocytic leukemia, and review related literature. Results Ordinary induction regimen can achieve good outcomes in this patient, but due to difficulty in nursing care and poor compliance, this kind of patient need further health education. Conclusion Infant acute promyeloeytic leukemia can be successfully treated with ordi- nary chemotherapeutical regimen, but health education is need for compliance.

关 键 词：急性早幼粒细胞白血病 全反式维甲酸 蒽环类药物 

分 类 号：R725[医药卫生—儿科]