271例甲型H1N1流感心肌酶学结果分析  

Analysis of serum cardiac muscle zymology in 271 patients with influenza A pandemic(H1N1)

作　　者：周晓飞[1] 刘大凤[1] 周凤先[1] 王玥莲[1] 陈定潜[1] 李青峰[1] 

机构地区：[1]成都市传染病医院,四川成都610061

出　　处：《临床肺科杂志》2012年第7期1174-1176,共3页Journal of Clinical Pulmonary Medicine

基　　金：四川省科技支撑计划项目(项目编号2010SZ0014);四川省中医药管理局中医药科技专项课题(项目编号:2009A02)

摘　　要：目的分析甲型H1N1流感心肌酶学的变化特征。方法分析我院2009年收治的271例甲型H1N1流感病例心肌酶学的变化。结果 1、随着疾病的加重,心肌酶CK、CK-MB及LDH均值明显升高,LDH异常例数明显增多,异常均值明显升高,组间比较有统计学意义(P<0.05);CK及CK-MB异常例数及异常均值随疾病加重而有所增加,但组间比较无明显统计学意义(P>0.05)。2、病毒转阴时心肌酶CK、CK-MB及LDH恢复则随疾病加重而减慢;LDH异常例数减少程度及异常均值下降幅度均随疾病加重而减慢,组间比较有统计学意义(P<0.05);随疾病的加重CK及CK-MB异常例数减少程度及异常均值下降幅度亦有所减慢,但组间比较无明显统计学意义(P>0.05)。结论甲型H1N1流感心肌酶学CK、CK-MB及LDH异常例数随疾病的加重而明显增多,异常均值随疾病加重而明显升高。Objective To analyze serum cardiac muscle zymology characteristics of 2009 influenza A （H1N1） in Si- chuan. Methods Dynamic changes of serum cardiac muscle zymology in 271 patients with influenza A pandemic （ H1 N1 ） admitted in 2009 were retrospective analyzed. Results （ 1 ） The basal creatine kinase （ CK）, ereatine phosphate isoenzyme （CK-MB） and lactate dehydrogenase （LDH） significantly increased along with the condition worsening. The number and the average value of abnormal LDH also significantly increased, with statistical difference between the groups （ P 〈 0. 05 ）. Although the number and the average value of abnormal CK and CK-MB increased, there was no significant deferences （ P 〉 0. 05 ）. （ 2 ） At the time of virus becoming negative, the ratio of recov- ery and the decrease degree of basal abnormal CK, CK-MB and LDH significantly reduced along with the condition worsening. There was statistical difference in LDH between the groups （ P 〈 0. 05 ）, but without statistical differences in CK and CK-MB （ P 〉 0. 05 ） . Conclusions The number and the average value of abnormal serum cardiac muscle zymology increase along with the condition worsening.

关 键 词：甲型H1N1流感 心肌酶 

分 类 号：R511.7[医药卫生—内科学]