益气养阴润肠方对小鼠肠道动力的影响  

Experimental study of Yiqiyangyinrunchang decoction on the mouse intestinal motility

作　　者：王云峰[1] 

机构地区：[1]江苏省昆山市第二人民医院消化科,江苏昆山215300

出　　处：《中国中西医结合消化杂志》2012年第5期214-215,218,共3页Chinese Journal of Integrated Traditional and Western Medicine on Digestion

摘　　要：[目的]研究益气养阴润肠方对小鼠肠道动力的影响。[方法]小鼠40只,随机分为益气养阴润肠方高剂量(47.84g·kg-1·d-1)组、中剂量(23.92g·kg-1·d-1)组、低剂量(11.96g·kg-1·d-1)组、正常组、新斯的明组(阳性组)。实验7d后处死所有小鼠,测碳末推进率。[结果]阳性组、益气养阴润肠方各剂量组的碳末推进率均明显提高,与正常组比较,差异有统计学意义(P<0.0 1)。[结论]中医益气养阴润肠法汤剂对小鼠肠道动力有明显的促进作用。[Objective]To study the effect of the decoction of Yiqiyangyinrunchang on the mouse intestinal motility. [Methods]Forty mice were randomly divided into Yiqiyangyinrunchang decoction of high（47.84 g ·kg^-1 · d^-1）,medium（23.92 g ·kg^-1· d^-1） ,low dose group（11.96 g · kg^-1· d^- 1）,normal group（0 g ·kg^-1· d^-1） 0. 00013 g · kg^-1 · d^-1）. Seven days after the ,positive group（Neostigmine, used in the last day, administration, the rate of carbon propelling was measured. [Results]Compared with the normal group, the positive group, Yiqiyangyinrunchang low dose group, middle dose and high dose group showed significantly increased carbon propel- ling, and had a statistically significant difference （P〈0.01）. [Conclusion] The decoction of Yiqiyangyinrunchang has significant promotion on intestinal motility of the mouse.

关 键 词：便秘 益气养阴润肠 肠道动力 实验研究 

分 类 号：R442.2[医药卫生—诊断学] R574.62[医药卫生—临床医学]