初步探讨糖尿病患者急性冠脉综合征的危险因素  

Preliminary Study of the Risk Factors of ACS in Patients with Diabetes

作　　者：秦爱华 孙健玲[2] 吴立华[2] 王崇禹[2] 师树田[2] 王娟[2] 

机构地区：[1]北京市延庆县大榆树镇社区卫生服务中心,北京102100 [2]航空总医院心内科,北京100012

出　　处：《中国医药导刊》2012年第5期739-741,共3页Chinese Journal of Medicinal Guide

摘　　要：目的:探讨糖尿病患者急性冠脉综合征的危险因素。方法:118例糖尿病患者(男66例,女52例),分为急性冠脉综合征组(65例)和非急性冠脉综合征组(53例);测量脉压(PP),查纤维蛋白原(FIB)、D-二聚体(D-Dimer)、空腹血糖(FBP)、糖化血红蛋白(HBA1C)、尿酸(UA)、肌酐(CREA)、血脂;入组患者均经冠脉造影确诊;所有数据均输入SPSS11.0软件包,并行T检验、非条件回归分析,了解糖尿病患者急性冠脉综合征的危险因素。结果:纤维蛋白原(FIB)、脉压(PP)与糖尿病患者急性冠脉综合征事件相关(P分别为0.017和0.000),回归值分别为0.990,0.884。结论:纤维蛋白原、脉压为糖尿病患者急性冠脉综合征的危险因素,通过降低纤维蛋白原水平和脉压差,有望预防糖尿病患者发生急性冠脉事件。Objective：To discuss the risk factors for ACS in diabetes mellitus.Methods：Divided 118 patients into two groups,one ACS group,another non-ACS group in diabetes mellitus;take down mean pulse pressure,test the serum level of fibrinogen,Ddiemer,Fasted Blood Glucose（FBP）,hemoglobin A1c（HBA1c）,uric acid（UA）,creatinine（CREA）.All patients have coronary arteriography;all the data are inputed into SPSS 11.0,analyse the data base T test or logistic regression;to confirm the relation between fibrinogen,pulse pressure,HBA1C,uric acid,creatinine and ACS in diabetes mellitus.Results：Fibrinogen,pulse pressure have positive correlation with ACS in diabetes mellitus,P value for one 0.017,another 0.000.Conclusion：Fibrinogen,pulse pressure are risk factors of ACS in diabetes mellitus.Maybe we can lower the level of fribrinogen and pulse pressure to reduce ACS in diabetes mellitus.

关 键 词：急性冠脉综合征 糖尿病 纤维蛋白原 脉压 

分 类 号：R541.4[医药卫生—心血管疾病] R587.1[医药卫生—内科学]