表浅性膀胱癌患者的循证治疗  

Evidence-based Treatment for Superficial Bladder Cancer

作　　者：许明伟[1] 张杰[1] 周晓光[1] 王伟[1] 程凯[1] 

机构地区：[1]武汉大学人民医院泌尿外科,武汉430060

出　　处：《医学综述》2012年第10期1587-1590,共4页Medical Recapitulate

基　　金：武汉大学博士生自主科研课题;中央高校基本科研业务费专项资金资助(20103020201000196)

摘　　要：目的针对1例表浅性膀胱癌患者,借助循证医学的方法进行证据检索和评价,寻找合适及有效的治疗方法。方法充分评估患者情况后,提出临床问题,计算机检索Pubmed(1998～2011年)、Cochrane图书馆(2011年第4期)、中国学术期刊全文数据库(1990～2011年)等,查找治疗表浅膀胱癌有关的系统评价、临床随机对照试验等,并对所获证据进行评价。结果纳入表浅膀胱癌治疗的随机对照试验29篇,系统评价或Meta分析27篇,根据所获证据给患者制订治疗方案。结论以高质量证据、结合患者情况制订治疗方案,能明显提高表浅性膀胱癌患者的近期疗效,但远期预后尚需更长时间的随访观察。Objective To find more appropriate and effective treatment for a patient with superficial bladder cancer in the aid of evidence-based medicine retrieval and evaluation. Methods After a full assess- ment of the patient,we attempted to get the evidence of methods to treat superficial bladder cancer by search- ing Pubmed（ 1998-2011 ） ,The Cochrane Library（ Issue 4,2011 ） and CNKI（ 1990-2011 ）. Results A total of 29 randomized controlled trials ,27 systematic reviews and meta-analysis were included. The treatment plan was developed accordingly. Conclusion The individualized treatment plan based on the high quality evi- dence and patient＇s condition is optimal for the short-term treatment of superficial bladder cancer. However, the long-term prognostic benefits need to be confirmed by continuous follow-up.

关 键 词：膀胱肿瘤 表浅性膀胱癌 卡介苗 循证治疗 

分 类 号：R453[医药卫生—治疗学] R694.7[医药卫生—临床医学]