台州地区体检人群乙型肝炎血清标志物结果分析  

Analysis of HBV serum makers results in health-examination population in Taizhou

作　　者：陈世勇[1] 王倩[1] 齐娟飞[1] 许玲鸽[1] 郭峰[1] 许成新[1] 

机构地区：[1]浙江省台州医院检验科,浙江台州317000

出　　处：《中国卫生检验杂志》2012年第5期1179-1180,1183,共3页Chinese Journal of Health Laboratory Technology

摘　　要：目的:了解台州地区健康体检人群乙型肝炎病毒(HBV)感染的变迁,以及实施计划免疫后对HBV感染率变化的影响。方法:对2003年-2009年HBsAg与HBsAb两项乙型肝炎病毒标志物结果进行回顾性分析。结果:2003年-2009年人群HBsAg阳性率逐步下降,HBsAb阳性率有升高趋势。男性HBsAg阳性率显著高于女性(χ2=372.8,P<0.05),HBsAb阳性率差别无统计学意义(χ2=0.017,P<0.05)。HBsAg阳性主要分布于31岁～50岁青壮年中。实施乙肝疫苗计划免疫后,18岁以下人群HBsAg阳性率下降显著,HB-sAb阳性率变化不明显。结论:自2003年-2009年,台州地区乙肝防治效果明显,儿童乙肝疫苗计划免疫对预防儿童感染HBV病毒效果显著,要继续加强实施。Objective：To investigate the change of Hepatitis B virus infection in Taizhou,and assess the HBV infection rate after the immunization program implementation.Methods： The detection results of HBsAg and HbsAb from 2003 to 2009 were analyzed by retrospective study.Results： From 2003 to 2009,the positive rate of HbsAg showed a downtrend,while that of HBsAb increased in seven investigated years.The positive rate of HBsAg in male was higher than that in female（χ^2=372.8,P〈0.05）,while HbsAb showed no significant difference（χ^2=0.017,P〈0.05）.Most positive HBsAg were found in young and middle-age men between 31~50.It also showed that the positive rate of HBsAg significantly dropped and HbsAb showed no difference in people below 18.Conclusion： From 2003 to 2009,the preventive work of HBV had an obvious effect in Taizhou,HBV vaccination for children is very significant in preventing them from infection,which should be strenghthen.

关 键 词：表面抗原 表面抗体 计划免疫 

分 类 号：R512.62[医药卫生—内科学]