系膜增生性肾小球肾炎患者血清IL-6、IL-10、IL-13检测的临床意义  

Clinical significance of determination of serum IL-6,IL-10 and IL-13 levels in patients with mesangial proliferative glomerulonephritis

作　　者：刘岩[1] 王桂成[1] 潘燕华[1] 

机构地区：[1]泰安市中心医院,山东泰安271000

出　　处：《现代医药卫生》2012年第10期1478-1479,共2页Journal of Modern Medicine & Health

摘　　要：目的探讨系膜增生性肾小球肾炎治疗前后血清IL-6、IL-10、IL-13水平的变化及意义。方法测定70例患者治疗前后血清IL-6、IL-10、IL-13的含量,并与30例正常健康者作比较。结果激素敏感组系膜增生性肾小球肾炎患者在治疗后血清IL-6、IL-10、IL-13水平较治疗前降低(P<0.05)。结论血清IL-6、IL-10、IL-13水平变化在一定程度上可提示病情变化,监测治疗效果。Objective To investigate the changes and clinical significance of serum interleukin-6（IL-6）,interleukin-10（IL-10） and interleukin-13（IL-13） levels before and after treatment in pediatric patients with mesangial proliferative glomerulonephritis.Methods Serum IL-6,IL-10 and IL-13 levels were determined in 70 patients before and after treatment and 30 controls.Results After treatment,the serum IL-6,IL-10 and IL-13 levels in the steroid sensitivity group were lower than those before treatment（P0.05）.Conclusion The changes of IL-6,IL-10 and IL-13 levels can reflect the change of disease condition and monitor the therapeutic effects.

关 键 词：白细胞介素6 白细胞介素10 白细胞介素13 肾小球肾炎 膜增生性 

分 类 号：R692.31[医药卫生—泌尿科学]