妊娠期肝内胆汁淤积症围产儿的血流检测与预后  

Study on the hemodynamics parameters in detection and prognosis of perinatal embryo with intrahepatic cholestasis of pregnancy

作　　者：张红薇[1] 王琦[1] 邵建兰[1] 李蕊[1] 董淑琳[1] 

机构地区：[1]川北医学院附属医院妇产科超声室,四川南充637000

出　　处：《医学影像学杂志》2012年第3期445-447,共3页Journal of Medical Imaging

摘　　要：目的评价彩色多普勒超声在预测妊娠期肝内胆汁淤积症(ICP)围产儿预后中的价值。方法检测46例ICP组及50例正常对照组胎儿脐动脉(UA)、大脑中动脉(MCA)及肾动脉(RA)血流阻力指标(S/D、PI、RI),计算PIMCA/PIUA值,并与妊娠结局对照。结果 37例单纯ICP胎儿UA、MCA、RA的S/D、PI、RI高于正常组;9例ICP并发胎儿宫内窘迫者,UA、RA的S/D、PI、RI明显高于正常组,而MCA的S/D、PI、RI明显低于正常组(P<0.01),预后不良。结论检测ICP胎儿多指标血流参数,以PIMCA/PIUA<2作为围产儿预后不良的预测指标,对预测胎儿宫内缺氧及不良结局有重要参考意义。Objective The study was to evaluate the value of colored Doppler in predicting the prognosis of perinatal embryo with intrahepatic cholestasis of pregnancy（ICP）.Methods Hemodynamics parameters（S/D,PI,RI） of fetal umbilical artery（UA）,middle cerebral artery（MCA） and renal artery（RA） were detected in 46 cases with ICP and 50 cases normal control group and the value of PIMCA/PIUA with the pregnancy result.Results S/D,PI,RI of UA,MCA,RA in the group of 37 cases with ICP were higher than those in normal group.In 9 ICP cases associated with fetal distress,S/D,PI,RI of UA,RA were obviously higher than those in normal group.But S/D,PI,RI of MCA were distinctly lower than the normal group（P0.01）,with poor prognosis.Conclusion To detect the multi-index hemodynamics parameters of ICP embryo,and to take PIMCA/PIUA2 as the predicting index of perinatal embryo with poor prognosis,the accordance rate was 89.2%.This has important reference significance for predicting the intrauterine fetal anoxia and bad results.

关 键 词：妊娠期肝内胆汁瘀积症 围产儿 彩色多普勒 血流参数 预后 

分 类 号：R714.25[医药卫生—妇产科学] R445.1[医药卫生—临床医学]