CT引导下^(125)I粒子永久植入治疗肝转移癌  

CT guided ^(125)I seeds interstitial permanent implantation as a treatment of liver metastasis

作　　者：范新华[1] 金利盛[1] 

机构地区：[1]浙江省义乌市中心医院放射科,浙江义乌322000

出　　处：《医学影像学杂志》2012年第4期581-584,共4页Journal of Medical Imaging

摘　　要：目的探讨CT引导下125I粒子植入治疗在肝转移癌治疗中的意义。方法 2007年8月～2008年10月31例结肠癌肝转移患者,共67个转移灶,均采用CT导向下125I放射性粒子植入,粒子植入之前采用治疗计划系统(treat-ment planning system,TPS)模拟布源或遵循Halarism的125I经验公式(mCi=Da×5),粒子按照0.5～1.0cm平面插植。在螺旋CT导向下将125I放射性粒子植入肝转移癌实质内及肿瘤边缘。结果治疗后2个月进行肿瘤影像学评价,31例患者中,完全缓解(complete remission,CR)7例,部分缓解(partial remission,PR)15例,稳定(no change,NC)9例。全组31例目前全部存活,随访时间最长14个月,最短6个月,近期平均生存期10.5个月。结论 CT导向下125I粒子植入治疗肝转移癌疗效确切、创伤小、并发症少,是一种比较安全、微创、有效的方法。Objective To analyze the clinical value of CT guided 125^Ⅰ seeds implantation in the treatment of liver metasta- sis. Methods The retrospective analysis was undertaken in 31 patients with 67 metastases from Aug. 2007 ro Oct. 2008. all the patients with liver metastasis caused by colorectal cancer were treated by CT guided 125^Ⅰ radioactive seeds implanta- tion according to TPSor Halarism＇s experienced function： mCi=DaXS, 125^Ⅰ seeds were implanted into at an interval of 0.5-1.0 cm according to treatment plan system. In spiral CT guided radioactive 125^Ⅰ seed implantation was berformed to the parenchyma of liver metastasis and tumor edge. Results All the patients undergo followed CT scan after 2 months. There ar 7 complete remission （CR）,15 partial remission （PR）, 9 stable disease （SD）. All patients are still alive now, the longest followed span is 14 months, and the shortest is. 6 months, the average followed span is 10.5 months. Conclu- sion CT guided 125^Ⅰ seeds implantation has good clinical results with minimal and few complications for treatmenting liver metastasis caused by eolorectal cancer, which is a relatively safe, minimally invasive and effective method.

关 键 词：肝转移癌 125I粒子 体层摄影术 X线计算机 

分 类 号：R814.42[医药卫生—影像医学与核医学]