抗癌药物新剂型—白蛋白微球5—氟脲嘧啶白蛋白微球的稳定性考查  

A New Type Dosage form of Antitumor Drugs-albumin Microspheres:Study on the physical Stability of 5-FU Albumin Microspheres

作　　者：张中和[1] 马星[1] 李军[2] 陈学文[2] 李炳生[3] 

机构地区：[1]兰州医学院药学系药剂教研室,730000 [2]兰州医学院药学系 [3]兰州医学院附一院药剂科,730000

出　　处：《中国医院药学杂志》1990年第6期262-264,共3页Chinese Journal of Hospital Pharmacy

摘　　要：本文报告了5—氟脲嘧啶白蛋白微球(5—FUAM)注射液的物理稳定性。以5—FUAM,吐温80及生理盐水组成的处方,在观察期限内沉降缓慢;经离心沉降后也易于分散。流通蒸气灭菌30min 及室温贮存50d 后,微球粒度略有增大。The physical stability of 5-FU Albumin Microspheres(5-FUAM)injectionwas studied.The sedimentation velocity of the suspending preperation,whichconsisted of 5-FUAM,tween and normal saline,was slow and dispersed quicklyin the duration of the observation.The size of 5-FUAM increased by sterilizationwith flow-steam for 30 min or store in room temperature for 50 days.

关 键 词：5-氟脲嘧啶 白蛋白 微球 稳定性 

分 类 号：R927.11[医药卫生—药学]