锯叶棕果实提取物治疗BPH引起的下尿路症状疗效观察  

Clinical efficacy of saw palmetto extract in the treatment of benign prostatic hyperplasia patients with lower urinary tract symptoms

作　　者：杨栋[1] 吴晓飞[1] 朱朝晖[1] 杨雄[1] 

机构地区：[1]华中科技大学附属协和医院泌尿外科,武汉430022

出　　处：《临床泌尿外科杂志》2012年第6期458-460,共3页Journal of Clinical Urology

摘　　要：目的:探讨锯叶棕果实提取物治疗BPH引起的下尿路症状的疗效。方法:采用锯叶棕果实提取物单药治疗30例前列腺增生伴下尿路症状患者8周,分别比较患者治疗前后的最大尿流率、前列腺体积、剩余尿量、IPSS评分及QOL评分的变化情况。结果:治疗8周后,患者的最大尿流率、剩余尿量、IPSS评分及QOL评分均有明显改善,前列腺体积则无明显变化。所有患者均无明显不良反应。结论:锯叶棕果实提取物能有效改善BPH患者的下尿路症状。Objective：To evaluate the clinical efficacy of saw palmetto extract in the treatment of benign prosta- tic hyperplasia（BPH） patients with lower urinary tract symptoms（LUTS）. Methods..30 BPH patients with LUTS were treated with saw palmetto extract 160mg twice a day for 8 weeks. We compared the maximum urinary flow rates（Q^ax）, Volume of the prostate（V）, International Prostate Symptom Scores（IPSS）, Quality of Life indexes （QOL） and post-void residual urine（PVR） before and after the treatment. Results.. After 8 weeks medication, the Qm,x, IPSS, QOL and PVR of the patients have significantly difference compared to which before the treatment. No patients experienced the adverse event. Conclusions： Saw palmetto extract is effective and safe in the treatment of BPH patients with LUTS.

关 键 词：前列腺增生 锯叶棕果实提取物 下尿路症状 

分 类 号：R697[医药卫生—泌尿科学]