急性下肢缺血介入治疗疗效的影响因素分析  

Analysis of impact factors of efficacy of endovascular therapy for acute lower limb ischemia

作　　者：张娣[1,2] 顾建平[1,2] 楼文胜[1,2] 何旭[1,2] 陈亮[1,2] 陈国平[1,2] 

机构地区：[1]南京医科大学附属南京医院 [2]南京市第一医院介入科,江苏南京210006

出　　处：《中国介入影像与治疗学》2012年第6期431-434,共4页Chinese Journal of Interventional Imaging and Therapy

基　　金：国家"十一五"科技支撑计划课题项目(2007BAI05B04)

摘　　要：目的探讨影响急性下肢缺血(ALI)介入治疗疗效的因素。方法回顾性分析我科收治的95例ALI患者资料,对可能影响治疗效果的因素进行分析。结果治疗总有效率为84.21%(80/95)。统计学检验结果显示合并高血压、合并外周动脉硬化性疾病、病变部位为多部位病变、Rutherford分级高、溶栓时间长的患者治疗效果较差。结论患者是否合并高血压、外周动脉硬化性疾病及病变部位、Rutherford分级及溶栓时间可影响介入治疗ALI的疗效。对于ALI患者应该尽早诊断及治疗,以提高治疗效果。Objective To assess impact factors of efficacy of intra-arterial thrombolysis and （or） adjuvant endovascular techniques for the treatment of acute lower limb ischemia （ALI）. Methods Totally 95 patients with ALI were enrolled, and the potential clinical impact factors affecting efficacy of endovascular therapy were analyzed. Results The effective rate was 84. 21% （80/95）. Hypertension, peripheral atherosclerotic disease, long-time thrombolysis, high-level of Rutherford classification and multi-site lesions negatively affected the efficacy of treatment. Conclusion Hypertension, peripheral ath- erosclerotic disease, lesion location, Rutherford classification and thrombolysis time negatively associate with efficacy of interventional treatment of ALI. Early diagnosis and early treatment are benefit for patients with ALI for improving therapeutic effect.

关 键 词：下肢缺血 急性 治疗 放射学 介入性 

分 类 号：R543[医药卫生—心血管疾病] R814.4[医药卫生—内科学]