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作 者:袁梅娟[1] 徐铭恩[1] 胡金夫[1] 杨敏[1]
机构地区:[1]杭州电子科技大学生物医学工程与仪器研究所,杭州310018
出 处:《生物医学工程学杂志》2012年第3期546-549,587,共5页Journal of Biomedical Engineering
基 金:国家自然科学基金资助项目(30600140);浙江省科技计划项目资助(2008C23007)
摘 要:股骨严重损伤是人类常见的骨骼疾病,重建股骨并分析其力学性能是人工股骨替代物研发的关键,然而传统的股骨假体置换往往会引起假体松动等现象。本研究选择健康人体股骨进行CT扫描,运用Mimics10.0软件建立了高精度的股骨原型并进行力学分析,然后选择具有良好生物相容性和可降解性的材料,采用低温沉积制造(LDM)技术进行股骨制造,获得了具有宏观股骨结构和良好微观孔隙结构的股骨支架,为后期股骨植入人体的研究奠定了基础。Serious femoral damages are a common human bone disease. Rebuilding the femur and studying its me- chanical properties are a continuous medical research topic, but traditional femoral prosthesis often cause some prob- lems such as prosthesis loosening. In this work, we selected a healthy male, took his femur scanning by CT, and re- built high-precision femur prototypes by Mimics10.0 software, then chose the material having good biocompatibility and biodegradable, utilizing low-temperature deposition manufacturing (LDM) technology for the femoral manufac- turing. This approach, fabricating the femur via LDM technology, laid a foundation for the later research on the femoral implantation in the human body.
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