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作 者:刘云[1] 向小勇[2] 都定元[1] 周继红[3] 张为民[1] 孔令文[1]
机构地区:[1]重庆市急救医疗中心,重庆市急救医学研究所胸心外科,400014 [2]重庆医科大学附属第一医院胸心外科 [3]第三军医大学附属大坪医院野战外科研究所
出 处:《中华创伤杂志》2012年第6期529-532,共4页Chinese Journal of Trauma
基 金:重庆市科委重大科技专项基金资助项目(CSTC,2008AA0011);重庆市科委应用基础研究基金资助项目(97-4714);重庆市卫生局医学科学技术研究重点资助项目(2010-1-52)
摘 要:目的分析严重胸部创伤(severechesttrauma,SCT)患者死亡相关危险因素。方法回顾性分析2006年1月-2009年4月重庆市急救医疗中心收治的777例SCT患者简明损伤评分(AIS)≥3分的资料,对影响患者死亡的15项可能危险因素进行多因素逐步Logistic回归分析。结果与SCT死亡相关的因素分别是年龄、失血性休克、MODS、肺部感染、腹腔脏器损伤、GCS值及胸AIS值。其中影响SCT患者死亡的最终独立危险因素包括失血性休克(B=1.710,OR=1.291,P〈0.01)、MODS(B=3.453,OR=1.028,P〈0.01)、肺部感染(B=2.396,OR=10.941,P〈0.01)、腹腔脏器损伤(B=1.542,OR=1.210,P〈0.01)和胸AIS≥3分(B=0.487,OR=1.622,P〈0.01);影响SCT患者死亡的保护因素包括年龄≤60岁(B=-0.035,OR=0.962,P〈0.05)、GCS≥12分(B=-0.635,OR=0.530,P〈0.05)。结论年龄、严重并发症、伤情准确诊断与评估是预测创伤后救治结局的相关因素;针对这些因素制定有效的治疗方案是提高SCT患者生存率的关键。Objective To investigate the risk factors affecting the mortality in patients with severe chest trauma (SCT). Methods A total of 777 patients with SCT (AIS≥3) treated at Chongqing Emer- gency Medical Center from January 2006 to April 2009 were involved for retrospective study. Multivariate stepwise Logistic regression analysis was used to analyze 15 possible risk factors affecting their mortality. Results The factors affecting mortality in patients with SCT included hemorrhagic shock (X6, B = 1. 710, OR = 1. 291, P 〈 0.01 ), multiple organ dysfunction syndrome (MODS) ( X7, B = 3. 453, OR = 1. 028, P 〈0.01 ), pulmonary infection ( xg, B = 2. 396, OR = 10. 941, P 〈 0.01 ), abdominal organ injury (Xll, B = 1.542, OR = 1.210, P〈0.01) and thoracic AIS≥3 (X14, B =0. 487, OR = 1. 622, P 〈 0.01). While the protective factors affecting mortality in patients with SCT contained age ≤60 years old (X1, B =- 0.035, OR =0.962, P〈0.05) and GCS≥12 (X13, B =- 0.635, OR =0.530, P〈0.05). Conclusions The age, posttraumatic complications (hemorrhagic shock, MODS, pulmonary infection) and accurate diagnosis and evaluation of trauma severity are the related factors to predict the prognosis. De- velopment of effective treatment measures based on these risk factors plays a key role in the survival rate of patients with SCT.
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