中枢5-羟色胺在针刺效应中的作用研究进展  

Progress of Researches on Involvement of Serotonin in the Central Nervous System in Acupuncture Analgesia and Other Effects

作　　者：胡吴斌[1] 吴子建[1] 汪克明[1] 

机构地区：[1]安徽中医学院针灸经络研究所,合肥230038

出　　处：《针刺研究》2012年第3期247-251,共5页Acupuncture Research

基　　金：国家自然科学基金(30801484);安徽省自然科学基金(090413112);安徽高校省级自然科学研究项目(KJ 2011A188);安徽中医学院科学研究基金(2010zr 016B)资助

摘　　要：5-羟色胺作为参与针刺效应的重要中枢调控物质,在阐述针刺效应作用机制中有着重要的研究价值。大量实验研究已证明针刺能显著影响中枢5-羟色胺的含量及活动,且不同条件下针刺对5-羟色胺影响不同。本文就近年来国内外中枢5-羟色胺及其受体在针刺效应中的作用研究现状作了回顾,并结合以往的研究提出新的看法和研究思路。As for an important central regulatory neurotransmitter involving acupuncture effect, serotonin（5-HT）is worthy of being paid with more attention. In the present paper, the authors review development of researches on the involvement of 5-HT and its receptor subunits in pain perception, acupuncture analgesia, and other effects of acupuncture （anti-depression, weight-re- duction, etc. ）. Many studies showed that acupuncture intervention could modulate the content and activity of central 5-HT, and these changes varied under different conditions. Hence, the relationship between 5-HT and other neurotransmitters in acupuncture analgesia and its different functions in different regions of the central nervous system should be considered comprehensively.

关 键 词：5-羟色胺 中枢神经系统 针刺镇痛 电针 

分 类 号：Q426[生物学—神经生物学]