46例注射用门冬氨酸洛美沙星药品不良反应/事件的分析  

作　　者：赖金华[1] 周学琴[1] 

机构地区：[1]北京大学深圳医院药剂科,518036

出　　处：《当代医学》2012年第17期128-130,共3页Contemporary Medicine

摘　　要：目的分析注射用门冬氨酸洛美沙星药物不良反应/事件(ADR/ADE)发生的类型及特点,为临床合理用药提供参考。方法对2008年1月1日～2011年7月30日收集到的46例注射用门冬氨酸洛美沙星ADR/ADE报告,从患者情况、不良反应的临床表现、原患疾病及因果关系的评价等方面进行回顾性统计分析。结果 46例注射用门冬氨酸洛美沙星ADR/ADE报告中,女性多于男性;累及的系统-器官主要是皮肤及其附件、消化系统、中枢神经系统、光敏反应、呼吸系统等;主要发生在用药后5～40min内,多数患者在停药后1d内康复或明显好转。结论应重视注射用门冬氨酸洛美沙星用药后的监护,减少或者避免严重ADR/ADE的发生,确保临床安全、有效、合理用药。Objective To analyze relevant factors of the adverse drug reactions/event（ADR/ADE） induced by LomefloxacinAspartate for Injection.Methods 46 Lomefloxacin Aspartate for Injection ADR/ADE Reports were statistical analyzed from Jan1.2008 to April30.2011 in our hospital.The condition of patients,clinical manifestations of adverse reaction,types of antibacterials and assessment were analyzed.Results 46 cases of ADR/ADE,females was slightly more than males.The clinical manifestation of ADR/ADE mainly involved system damage,skin and appendages damage,digestive and respiratory system damage.ADR/ADE usually occurred between 5 to 40 min after administration.Most ADR /ADE cases happened in one day after medication.Conclusion The patients should be intensively warded after the first medication.It is important to diagnose correctly and disposal in time to the ADR/ADE and rational use of drugs.

关 键 词：注射用门冬氨酸洛美沙星 药品不良反应 事件 分析 

分 类 号：R978.1[医药卫生—药品]