推注速度对罗哌卡因复合舒芬太尼蛛网膜下腔麻醉效果的影响  

Different injection rates of isobaric ropivacaine combined with sufentanil on the effect of spinal anesthesia

作　　者：贺亮[1] 徐军美 

机构地区：[1]中南大学湘雅二医院麻醉科,长沙市410011

出　　处：《临床麻醉学杂志》2012年第5期439-441,共3页Journal of Clinical Anesthesiology

摘　　要：目的研究不同推注速度对罗哌卡因复合舒芬太尼蛛网膜下腔麻醉效果的影响。方法选取2009年6月至2010年12月行前列腺电切手术老年患者60例,ASAⅡ级,随机均分为Ⅰ、Ⅱ两组,推注速度分别为0.3ml/s、0.05ml/s。观察两组在推注局麻药物前后的血流动力学变化情况、感觉阻滞起效时间、感觉阻滞最高平面、感觉阻滞持续时间及痛觉阻滞不全、恶心、呕吐、蛛网膜下腔阻滞后暂时性神经症状等不良反应发生情况。结果两组患者血流动力学变化情况、最高感觉阻滞平面、感觉阻滞达到T10平面时间、感觉阻滞自最高平面下降两个节段的时间、运动阻滞评分、各种不良反应发生率差异均无统计学意义。结论推注速度可能不会对等比重局麻药物蛛网膜下腔阻滞的麻醉效果产生临床可见的影响。Objective To investigate different injection rates of isobaric ropivacaine combined with sufentanil on the effect of spinal anesthesia. Methods Sixty patients（≥65 years, ASA grades） undergoing transurethral surgery under spinal anesthesia were allocated randomly into two groups according to rate of intrathecal injection of 1.5 ml isobaric ropivacaine 0. 5%： injection rate 0.3 ml/s （group 1 ,n=30） and injection rate 0.05 ml/s, （group Ⅱ ,n=30）. Hemodynamics, the anesthetic level, time to the emerge of anesthetic level, duration of paresthesia, the incidence of inadequate anesthesia, nausea, vomiting and transient nervous dysfunction were recorded. Results There was no significant difference between the two groups with regard to hemodynamics, maximum sensory anesthetic level, time when sensory anesthetic level to T10 , 2-segment regression of anesthesia, the degree of motor block, and other adverse effects. Conclusion The injection rate of isobaric local anesthetic has no clinical effect on spinal anesthesia.

关 键 词：蛛网膜下腔麻醉 推注速度 罗哌卡因 舒芬太尼 

分 类 号：R614[医药卫生—麻醉学]