孕前体质指数与4种不良妊娠结局关系  

Relationship between pre-pregnancy BMI and adverse birth outcomes

作　　者：楚舟[1,2] 陶芳标[1,2] 郝加虎 宫相君[1,2] 徐蓉 孙露[1,2] 刘芳 

机构地区：[1]安徽医科大学公共卫生学院儿少卫生与妇幼保健学系,安徽合肥230032 [2]安徽人口健康与优生省级实验室

出　　处：《中国公共卫生》2012年第6期763-766,共4页Chinese Journal of Public Health

基　　金：国家"十一五"科技支撑计划重大项目(2006BAI05A03)

摘　　要：目的探讨孕前体质指数(BMI)与4种不良妊娠结局(小于胎龄儿、大于胎龄儿、低出生体重儿、巨大儿)的关系。方法以2008年10月—2010年10月在安徽省8个地市的妇幼保健机构孕早期建卡并随访到分娩记录的12 355名孕妇为对象,采用χ2检验和非条件Logistic回归分析模型,分析孕前BMI与4种不良妊娠结局的关系。结果孕妇孕前BMI均数为(20.19±2.348)kg/m2,过低2 834人(22.9%),正常8 745人(70.8%),超重及肥胖776人(6.3%);调整年龄、户籍地、孕次等混杂因素后,对孕前BMI与胎龄儿组和体重儿组分别进行关联性分析,结果显示,孕前BMI过低是发生小于胎龄儿的危险因素(OR=1.320,95%CI=1.068～1.631);孕前超重及肥胖是发生大于胎龄儿和巨大儿的危险因素(OR=1.758,95%CI=1.503～2.056;OR=1.870,95%CI=1.540～2.271)。结论孕前BMI过低或者过高均会影响妊娠结局。Objective To assess the relationships between pre-pregnancy body mass index（BMI） and the 4 adverse birth outcomes,including small for gestational age（SGA）,large for gestational age（LGA）,low birth weight（LBW）,and macrosomia.Methods Subjects were 12 355 pregnant women who had joined in the Anhui Birth Defects and Child Development Cohort Study and delivered between October 2008 and October 2010.The relationships between pre-pregnancy BMI and SGA,LGA,LBW and macrosomia were evaluated by Chi-square analysis and non-conditional logistic regression.ResultsThe average pre-pregnancy BMI for the pregnant women was 20.19（2.348 kg/m2）.Based on the pre-pregnancy BMI,2 834 women were classified as underweight（22.9%）,8 745 as normal（70.8%）,and 776 as overweight or obese（6.3%）.After adjusted for confounding factors such as age,registered residence,and pregnant times,we figured out the relationship between pre-pregnancy BMI and the gestational age group and the birth weight group.Pregnant underweight increased the risk of SGA（odds ratio（OR）=1.320,95% confidence interval（CI：1.068-1.631）,pre-pregnant overweight and obesity increased the risks of LGA（OR=1.758,95% CI：1.503-2.056）and macrosomia（OR=1.870,95%CI：1.540-2.271）.Conclusion High or low pre-pregnancy BMI could effect birth outcomes.

关 键 词：体质指数 大于胎龄儿 小于胎龄儿 

分 类 号：R172[医药卫生—妇幼卫生保健]