四甲基碳酸氢铵的绿色合成工艺  

Green Synthesis of Tetramethylammonium Hydrogen Carbonate

作　　者：张桂菊[1] 徐宝财[1] 水金环[1] 韩富[1] 周雅文[1] 

机构地区：[1]北京工商大学食品学院北京市食品风味化学重点实验室食品添加剂与配料北京市高等学校工程研究中心,北京100048

出　　处：《精细化工》2012年第6期584-587,共4页Fine Chemicals

基　　金：国家自然科学基金资助项目(20976003;21176004);北京市属高校人才强教计划资助项目(PHR200906109);北京市优秀人才培养资助项目(2011D005003000013)~~

摘　　要：以碳酸二甲酯和三甲胺水溶液为原料,一步合成四甲基碳酸氢铵,主要考察了原料摩尔比、反应温度、反应时间对产物收率的影响。当碳酸二甲酯与三甲胺摩尔比为1:1.2、反应温度105℃、反应时间为5 h时,四甲基碳酸氢铵的收率达93.0%。Tetramethylammonium hydrogen carbonate was synthesized directly from dimethyl carbonate and trimethylamine in water. The effects of materials＇ molar ratio,reaction temperature and time on the yield of the product were investigated. The optimum reaction conditions were ascertained as follows ： the molar ratio of dimethyl carbonate to trimethylamine was 1 ： 1.2, the reaction temperature was 105 ℃, and the reaction time was 5 h. Under such optimum reaction conditions the yield of the product reached 93.0%.

关 键 词：四甲基碳酸氢铵 碳酸二甲酯 三甲胺水溶液 绿色合成 医药与日化原料 

分 类 号：TQ226.3[化学工程—有机化工]