幼年型类风湿性关节炎52例临床分析  

A clinical analysis of 52 cases with juvenile rheumatoid arthritis

作　　者：马家明[1] 鹿玲[2] 

机构地区：[1]安徽省肥西县人民医院儿科,安徽肥西231200 [2]安徽医科大学第一附属医院儿科,安徽合肥230022

出　　处：《安徽医药》2012年第6期799-800,共2页Anhui Medical and Pharmaceutical Journal

摘　　要：目的探讨幼年型类风湿性关节炎(JRA)的临床特点,减少误诊误治。方法回顾性分析52例JRA患儿临床特征、实验室检查、影像学检查及治疗转归情况。结果 JRA多见于男性患儿,年龄大多在学龄儿童。52例JRA中,全身型占65.5%,多关节型和少关节型占34.5%;实验室检查缺乏特异性;关节的彩色多普勒超声检查是JRA诊断及评价疗效的重要辅助检查;治疗上加用激素治疗者较单纯NSAIDS治疗者临床症状缓解快,甲氨蝶呤(MTX)作用肯定且安全。结论 JRA的临床表现以发热、皮疹、关节痛为主,全身型多器官受损明显。治疗上首选NSAIDS,其次可加用激素。JRA的总体预后不乐观。Objective To explore the clinical characteristics of juvenile rheumatoid arthritis（JRA） , and to reduce misdiagnosis and mis- treatment. Methods The data of 52 cases of JRA were retrospectively analyzed for clinical characteristics, laboratory examination, ima- ging examination and therapeutic outcomes. Results JRA was commonly seen in male children and the common age was school chil- dren. There were 65.5 percent of Sys-JRA ,34.5 percent of polyarticular and pau-ciarticular juvenile rheumatoid arthritis in 52 patients. No laboratory test was specific. Color doppler ultrasonography with articular was an important auxiliary examination in diagnosis of JRA and evaluation of the efficacy. The clinical manifestations were relieved faster in the cases of combined treatment with hormone than non- steroidal anti-inflammatory drugs（ NSAIDs） treatment only. The action of MTX was positive and safe. Conclusion Clinical characteris- tics of JRA are fever, anthema, arthrosis pain. There are multi organs obviously damaged in Sys-JRA. NSAIDsis the first choice for treat- ment and hormone can be added. General prognosis of JRA is not optimistic.

关 键 词：儿童 幼年型类风湿性关节炎 临床表现 彩色多普勒超声 

分 类 号：R725.9[医药卫生—儿科]