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作 者:康阿龙[1] 张娴[1] 黄黎明[1] 孙成荣[2] 马金强[1]
机构地区:[1]解放军第四五一医院,陕西西安710054 [2]解放军第三二三医院,陕西西安710054
出 处:《中国药物警戒》2012年第6期360-362,共3页Chinese Journal of Pharmacovigilance
基 金:国家科技支撑计划课题(2006038086056);"重大新药创制"科技重大专项子课题(2009ZX09502-030)
摘 要:目的对丹红注射剂临床应用的安全性进行再评价。方法采用集中主动监测法,监测我院2011年1月至10月中700例住院患者的用药情况、患者信息及发生的不良反应。结果共涉及8个科室的700个病例,16种疾病,不良反应3例,占0.43%(偶见);老年人使用比例占73.71%;不合理用药105例,占15.00%。结论丹红注射剂临用应用不良反应发生率低,安全性较高;不合理用药给临床用药安全增加了风险,应加强中药注射剂临床合理使用监管。Objective To evaluate the clinical safety of the Danhong injection. Methods Medication and Patient data and ADIL of 700 cases of Danhong Injection in our hospital were collected by active centralized minitoring during the period of January and October 2011. Results Based on the 700 inpatient cases which involved 8 departments and 16 rinds of diseases, whilst ADR occurred in 3 cases(0.43% of the total). 73.71% of the injection-takers were old patierits, 105 cases of the medication is unreasonable, accounting for 15.00%. Condusion A low incidence of ADR for the Danhong injection in its clinical application was found. Irrational drug use can increase safety risk. We should strengthen the supervision of clinical rational use of traditional Chinese medicine injections.
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