肾动脉支架置入治疗肾血管性高血压  

Renal Artery Stent Placement for the Treatment of Renovascular Hypertension

作　　者：蒋雄京[1] 吴海英[1] 明广华[1] 王静[1] 王蕾礼[1] 郑德裕[1] 刘国仗[1] 刘力生[1] 

机构地区：[1]中国医学科学院

出　　处：《中国循环杂志》2000年第1期27-28,共2页Chinese Circulation Journal

摘　　要：目的 :评估支架置入治疗肾血管性高血压的安全性和疗效。　　方法 :4例患者 ,男 1例 ,女 3例 ,年龄 3 9.5± 19.1岁 ,患有严重的肾动脉狭窄 ( 5条病变 ) ,因单用高压球囊扩张效果不满意 ,置入球囊扩张支架。　　结果 :5条狭窄肾动脉预扩张支架置入后 ,1条病变残余狭窄 10 % ,其余 4条病变无残余狭窄。 4例患者血压均有明显下降 ,收缩压从 15 7± 12 mm Hg( 1mm Hg=0 .13 3 k Pa)降至 12 8± 9mm Hg;舒张压从 95± 8mm Hg降至 81± 5mm Hg。 2例停用降压药物血压仍正常。另 2例降压药从 4种减至 2种 ,血压仍能满意控制。　　结论 :肾动脉支架置入是治疗肾血管性高血压的安全有效方法 ,其远期疗效需进一步随访调查。Objectives:To evaluate the safety and efficacy of stent placement in patients with poorly controlled hypertension caused by renal artery stenosis. Methods:Four patients,1 man and 3 women,aged 14—56 years(39.5±19.1),suffered from severe renal artery stenosis.Balloon expandable stents were placed in 5 arteries (diameter reduction 80%—100%),who had not been satisfactorily treated by high pressure balloon angioplasty. Results:Angiographic success(remained stenosis 10% in 1 lesion and 0% in 4 lesions) was obtained in 5 artery lesions.Early clinical improvement was seen all patients.Their mean systolic blood pressure was reduced from 157±12 mmHg to 128±9 mmHg;the diastolic blood pressure from 95±8 mmHg to 81±5 mmHg.Two of four patients who discontinued to take hypertensive medications maintained their blood pressure at normal level while other two patients reduced the hypertensive medications from four kinds to two still controlled their blood pressure satisfactorily. Conclusion:In this study the renal artery stenting appears to be an effective and safe treatment for renovascular hypertension.The long term outcomes remain to be investigated.

关 键 词：肾血管性高血压 肾动脉支架置入 

分 类 号：R544.140.5[医药卫生—心血管疾病] R654.3[医药卫生—内科学]