微波辐射下阳离子交换树脂催化合成对硝基苯甲酸乙酯  

Synthesis of p-nitro-ethylbenzoate catalyzed by cation exchange resin under microwave irradiation

作　　者：赵志刚[1] 邵太丽[1] 秦国正[1] 

机构地区：[1]皖南医学院药学系,安徽芜湖241002

出　　处：《应用化工》2012年第6期968-970,974,共4页Applied Chemical Industry

基　　金：安徽省教育厅自然科学研究项目(KJ201IZ397)

摘　　要：以对硝基苯甲酸和乙醇为原料,H-732强酸性阳离子交换树脂为催化剂,在微波辐射条件下合成对硝基苯甲酸乙酯,探讨了微波功率、醇酸摩尔比、催化剂用量、反应时间对产品产率的影响。结果表明,H-732强酸性阳离子交换树脂在微波辐射条件下对酯化反应有良好的催化能力;醇酸摩尔比为3∶1,催化剂用量为对硝基苯甲酸质量的20%,反应时间15 min,微波功率为250 W时,对硝基苯甲酸乙酯的产率最高为87.45%,催化剂可以重复使用,再生后催化性能保持良好。The p-nitro-ethylbenzoate was synthesized from p-nitrobenzoic acid and ethanol under micro- wave irradiation using strong-acid cation exchange resin H-732 as catalyst. The effect of microwave power, catalyst amount, reaction time and the molar ratio of ethanol to acid on the yield was investigated. The re- sults showed that strong-acid cation exchange resin H-732 had good catalytic activity to esterification un- der microwave irradiation. When the molar ratio of ethanol to acid was 3 ： 1, the amount of catalyst was 20% ofp-nitrobenzoic acid, the reaction time was 15 min, and the microwave power was 250 W, the yield of p-nitro-ethylbenzoate was 87.45%. The catalyst can be repeated used and has good catalytic capability after activation.

关 键 词：对硝基苯甲酸乙酯 微波辐射 阳离子交换树脂 合成 

分 类 号：TQ460.3[化学工程—制药化工] O621.3[理学—有机化学]