陕西省川崎病流行病学调查研究  

Epidemiological and clinical characteristics of Kawasaki disease in Shanxi province

作　　者：焦富勇[1] 杨丽芳[1] 乔荆[1] 李月华[1] 张拓红[2] 柳川洋 川崎富作 

机构地区：[1]陕西省人民医院儿科,西安710068 [2]北京医科大学 [3]日本自治医科大学公共卫生系 [4]日本川崎病研究所

出　　处：《中华流行病学杂志》2000年第2期97-99,共3页Chinese Journal of Epidemiology

摘　　要：目的　了解陕西省川崎病的实际发病情况、分布及流行病学现状。方法　采用日本中国川崎病流行病学调查组 1998年东京会议制定的统一标准 ,对 10 0张床位以上的二级甲等医院的15 0家儿科发出统一制定的流行病学调查表 ,选择 1993年 1月～ 1997年 12月儿科住院的川崎病初诊患儿进行登记调查。结果　调查表回收率 70 % ,5年间共报告患者 376例 ,男女之比 1.6 1∶1;发病年龄以 3岁以下为主 ,占 6 9% ;死亡率 1% ;发生心脏后遗症共 70例 ,占患者总数的 18.6 2 % ,男女之比为 3.1∶1,年龄越小 ,心脏后遗症的发病率越高 ,以冠状动脉扩张及冠状动脉瘤为主 ;在病后 6d确诊者较少 ,且城市大医院病例数多 ,边远地区病例数少。结论　川崎病是我省儿童较常见的疾病 ,西安地区是高发病区 ,3岁以下发病率高 ,心脏后遗症多。提示川崎病的研究目前已经成为儿科心血管领域的重要课题。应提高广大基层医师对该病的认识 ,做到早诊早治 。Objective The objective of this paper is to describe the epidemiological and clinical characteristics of Kawasaki disease (KD) in Shanxi province, China during a 5 year-period from January 1993 to December 1997. Methods A province-wide epidemiological survey on Kawasaki disease (KD) was carried ont by the China-Japan Kawasaki disease study group. The questionnaire form and the diagnostic criteria of KD which was prepared by the Japan Kawasaki disease research committee and translated into Chinese were sent of the departments of pediatrics of all the hospitals with 100 or more beds in Shanxi province. All the KD patients who were diagnosed during the observation period from 1993 to 1997 were asked to report to this survey. The database of reported KD in this survey was analyzed at the Department of pediatrics of the Shanxi provincial people′s hospital, Xian, China. All the patients that satisfied the diagnostic criteria were included. Results A total of 105(70%) hospitals responded and 376 cases of KD were confirmed. More cases were reported in 1993 and 1994. Of the total patients reported, 69% were children under 3 years old with male to female ratio of 1.6∶1. The proportion of patients with cardiac sequelae was 19% with male to female ratio: 3∶1. There were 4 fatal cases with a fatality rate of 1%. Conclusions Since KD is common in China continuous surveillance is necessary to maintain high awareness of KD so as to identify possible risk factors and its association with other disease.

关 键 词：川崎病 流行病学 陕西 

分 类 号：R181.3[医药卫生—流行病学]