喜炎平治疗儿童手足口病126例临床疗效分析  

Clinical Observation on Xiyanping Injection in Treating 126 Children with Hand,Foot,and Mouth Disease

作　　者：王成秀[1] 陈静[1] 王斌[1] 王智慧[1] 

机构地区：[1]重庆市第五人民医院,重庆400062

出　　处：《儿科药学杂志》2012年第6期32-33,共2页Journal of Pediatric Pharmacy

摘　　要：目的:了解喜炎平治疗儿童手足口病的临床疗效。方法:231例手足口病患儿随机分为两组,治疗组126例给予喜炎平注射液,对照组105例给予利巴韦林注射液,均为10 mg/kg静脉滴注,1次/d,疗程3 d。结果:治疗组退热及退疹时间、总病程均短于对照组;总有效率治疗组96.03%,对照组79.05%,两组比较差异有统计学意义(P<0.01)。结论:喜炎平治疗手足口病疗效明显优于利巴韦林,无明显不良反应,值得推广应用。Objective：To study the effect of Xiyanping in the treatment of hand, foot and mouth disease in Children. Methods： Randomly 231 infants with hand, foot and mouth disease were divided into a treatment group （ 126 cases） and a control group （ 105 cases）. The treatment group was given Xiyanping injection, while the control group was given ribavirin injection. The dosages of both groups were 10 mg/kg intravenously, one time a day, for 3 days. Clinical symptoms and the signs of change were observed. Results： The time to defervescence, the time to healing of the rash, and the course of disease in the treatment group were significantly shorter than those in the control group. The total efficiencies of the treatment group and the control groups were 96.03% and 79.05% , respectively, the differences of the two groups were significant （P〈0.01）. Conclusions： Xiyanping injection in the treatment of hand, foot, and mouth disease in children is an effective treatment. It is a safe treatment without toxic side effects.

关 键 词：手足口病 喜炎平 儿童 

分 类 号：R725.1[医药卫生—儿科]