特拉唑嗪及与双氯芬酸钠联合治疗CP/CPPS的研究  

The Research of Terazosin Hydrochloride Combined with Diclofenac Sodium in Treatment of CP / CPPS

作　　者：徐勇[1] 

机构地区：[1]南华大学附属第一医院,湖南衡阳421001

出　　处：《现代临床医学》2012年第3期171-173,共3页Journal of Modern Clinical Medicine

摘　　要：目的:比较单用特拉唑嗪与特拉唑嗪联合双氯芬酸钠治疗慢性前列腺炎/慢性骨盆疼痛综合征(CP/CPPS)的效果。方法:将106例CP/CPPS患者随机分为2组,A组予特拉唑嗪治疗(2 mg/d),B组予特拉唑嗪(2 mg/d)加双氯芬酸钠(25 mg/d)治疗。采用美国国立卫生研究所慢性前列腺炎症状评分(NIH-CPSI)、亚评分(疼痛及生活指数)及国际前列腺症状评分(IPSS)标准评价患者治疗8周后的效果。结果:2组治疗后的NIH-CPSI、亚评分及IPSS均明显减少,且2组之间评分无显著性差异。结论:特拉唑嗪单独治疗与联合双氯芬酸钠治疗CP/CPPS的效果相当。Objective ：To compare terazosin monotherapy with terazosin plus diclofenac in treatment of chronic prostatitis/ chronic pelvic pain syndromes （CP/CPPS） following initial randomness. Methods： Patients （n = 106） who were diagnosed with CP/CPPS were randomly assigned to treatment with terazosin at 2 mg（ group A）, terazosin at 2 mg plus diclofenac at 25 mg （group B） daily. National Institutes of Health -Chronic Prostatitis Symptom Index （NIH -CPSI）, subscores and the International Prostate Symptom Score （IPSS） were used to evaluate 104 patients who were treated for 8 weeks （2 withdrew）. Results：The two groups all showed statistically difference before and after treatment, decreased in NIH - CPSI score, subscore and IPSS （P 〈 0.05 ）. There were no statistically differences between the two groups. Conclusion： Terazosin monotherapy for 8 weeks is effective for treating patients with CP/CPPS same as with diclofenac.

关 键 词：特拉唑嗪 双氯芬酸钠 慢性骨盆疼痛综合征 治疗 

分 类 号：R697.33[医药卫生—泌尿科学]