1例克林霉素药源性发热分析和文献复习  

One case of clindamycin-induced hyperthermia and the review of drug-induced hyperthermia

作　　者：方忠宏[1] 曾宏辉[1] 张军[1] 王吉平[2] 

机构地区：[1]复旦大学附属金山医院药剂科,上海200540 [2]复旦大学附属金山医院护理部,上海201508

出　　处：《临床药物治疗杂志》2012年第3期58-60,62,共4页Clinical Medication Journal

摘　　要：药源性发热(drug-induced hyperthermia)是常见的药源性损害之一,抗菌药物引起药源性发热较常见,故在病情不危急却有发热的情况下,不应盲目大量地使用抗菌药物。否则,可能掩盖病因,加重病情,重者危及生命。Human life is a form of mutualistic symbiosis between human cells and microorganisms colonizing the skin, the gut and various natural openings. Drug-induced hyperthermia is one of drug-induced impairments. Since hyperthermia induced by antibacterials is more common than most of other drugs, it is advisable that antibacterials must not be administered blindly in patients with fever if not emergency. The unnecessary administration of antibacterials may cover the original cause of the illness, make the condition worse, and induce deadly harms.

关 键 词：克林霉素 药源性发热 抗菌药物 氨基糖苷类 药物损害事件 欣弗事件 

分 类 号：R595.3[医药卫生—内科学]