中西医结合治疗老年性痴呆的临床疗效探讨  

Clinical analysis of treatment of Alzheimer's disease by the integrated traditional Chinese and western medicine

作　　者：王明华[1] 罗榕[1] 梁晶晶[1] 

机构地区：[1]峨眉山市人民医院,四川峨眉山614200

出　　处：《西部医学》2012年第6期1105-1106,1109,共3页Medical Journal of West China

摘　　要：目的探讨中西医结合治疗老年性痴呆(AD)的临床疗效。方法将90例老年性痴呆患者随机分为对照组45例,采用常规西药治疗;治疗组45例,在常规西药治疗基础上加用中药方剂治疗。采用简易智能精神状态量表(MMSE)对治疗前后评分,比较治疗前后患者智能精神状态和治疗总有效率。结果治疗组45例,MMSE评分治疗前(14.34±1.85)分,治疗后(19.28±2.13)分,总有效率86.67%;对照组45例,MMSE评分治疗前(15.12±1.74)分,治疗后(16.75±2.14)分,总有效率73.33%。组间差异有统计学意义(P<0.05)。结论采用中西医结合治疗老年性痴呆,能改善患者的记忆功能和思维能力,延缓大脑的衰老过程,激活和提高大脑的智能水平,可提高患者的生活质量,值得临床推广应用。Objective To analyze the clinical effect of combined therapy of Chinese and western medicine in Alzheimer＇s disease. Methods 90 cases of senile dementia （AD） patients were randomly divided into the treatment group and the control group. The control group used conventional treatment, the treatment group used traditional Chinese at the basic therapy of the control group. The clinical effect before and after treatment was evaluated with Mini-Mental Status Scale （MMSE）. The mental state and the total effective rate before and after treatment were observed. Results MMSE score before and after treatment of the treatment group was 14.34± 1.85 and 19.28±2.13, with the total effective rate of 86.67%. MMSE score before and after of the control group treatment was 15.12±1.74 and 16.75±2.14, with the total efficiency of 73.33%. The above differences were statistically signitficant （P〈0. 05 ）. Conclusion The integrated traditional Chinese and western medicine to treat AD can improve the patients memory function and thinking ability, delay the brain aging process, improve the brain activation, intelligent level and patients quality of life.

关 键 词：中西医结合 老年性痴呆 简易智能精神状态量表 

分 类 号：R743.9[医药卫生—神经病学与精神病学]