中西医结合一体化管理模式对冠心病及其危险因素的影响  

Effect of integration management mode on coronary heart disease and its risk factors

作　　者：杨建梅[1] 张慧[1] 缪培智[1] 徐新春[1] 

机构地区：[1]上海市徐汇区中心医院中医科,上海200031

出　　处：《上海中医药杂志》2012年第6期26-28,共3页Shanghai Journal of Traditional Chinese Medicine

基　　金：上海市卫生局中医药科研基金资助项目(2009S035)

摘　　要：目的观察一体化管理模式对冠心病及其危险因素的影响。方法将200例气虚血瘀型、痰阻心脉型、气阴两虚型冠心病患者随机分为治疗组(105例)和对照组(95例);对照组采用西医常规治疗(口服硝酸异山梨酯片、拜阿司匹林等),治疗组在采用西医常规治疗基础上进行一体化管理模式管理(根据中医证型进行中医辨治,并制定健康管理计划,进行健康保健指导)。两组均治疗12周,观察临床症状、心电图、血压、胆固醇、三酰甘油、低密度脂蛋白、血糖的变化情况。结果①治疗组、对照组心电图疗效总有效率分别为66.1%、62.3%;组间心电图疗效比较,差异无统计学意义(P>0.05)。②治疗组和对照组各项中医证候评分治疗前后组内比较,差异均有统计学意义(P<0.01);组间比较,各指标评分差值差异均有统计学意义(P<0.01)。③两组治疗前后组内比较,收缩压、舒张压、胆固醇、三酰甘油、低密度脂蛋白及血糖水平差异均有统计学意义(P<0.01);组间治疗后比较,舒张压、胆固醇、三酰甘油、低密度脂蛋白及血糖水平差异有统计学意义(P<0.05)。结论中西医结合一体化管理模式可以改善气虚血瘀型、痰阻心脉型、气阴两虚型冠心病患者临床症状、心电图改变及冠心病相关危险因素。Objective To observe the effect of integration management mode on coronary heart disease and its risk factors. Methods Two hundred eases with cor onary heart disease of different types were randomized into two grnups： treatment group in which 105 cases were treated by routine treatment with integration man- agement mnde, and control group in which 95 cases were treated by routine treatment, with the course of 12 weeks. The clinical symptoms, ECG, blood pressure, cholesterol, TG, LDL aml blood sugar were measured. Results ①The overall ECG effective rate was 66.1% in the treatment group and 62.3% in the cnntrol group, with no significant difference between the two groups（ P 〉 0.05）. ②The syndrome scores in treatment group or control group were different significantly be- tween hefore and after treatment （ P 〈 0.01 ） ; there was significant difference in indexes between the two groups （ P 〈 0.01 ）. ③The systolic pressure, diastolic pressure, TC, LDL and blood sugar in treatment group or control group were diffrent significantly between before and after treatment （ P 〈 0.05 ）. Combined Chi- nese-western medicine with integration management mode can improve the clinical symptoms and ECG and decrease the risk factors in patients with coronary heart disease of three dif＇teren! types.

关 键 词：冠状动脉粥样硬化性心脏病 中西医结合一体化管理模式 危险因素 临床研究 

分 类 号：R541.4[医药卫生—心血管疾病]