苯丙醇类抗生素对蛋白核小球藻生长的影响  

Growth inhibition effect of phenicol antibiotics on Chlorella pyenoidosa

作　　者：李霞[1] 陈菊芳[1] 吕颂辉[1] 岑竞仪[1] 

机构地区：[1]暨南大学生命科学技术学院赤潮与水环境研究中心,广东广州510632

出　　处：《暨南大学学报（自然科学与医学版）》2012年第3期294-299,共6页Journal of Jinan University(Natural Science & Medicine Edition)

基　　金：国家自然科学基金项目(40471118);广东省自然科学基金项目(8151063201000053)

摘　　要：采用光照培养箱室内培养法,将蛋白核小球藻暴露于不同质量浓度苯丙醇类抗生素的水体中4 d,研究3种苯丙醇类抗生素氟苯尼考(FF)、甲砜霉素(TAP)和氯霉素(CAP)对蛋白核小球藻种群生长的影响.研究结果表明:氟苯尼考、甲砜霉素和氯霉素对蛋白核小球藻的生长有一定的抑制作用,该效应表现出一定的质量浓度和时间依赖性,48 h的EC50分别为10.42 mg/L、84.35 mg/L和28.66 mg/L;96 h的EC50依次为9.40、64.92和25.26mg/L.氟苯尼考、甲砜霉素和氯霉素对蛋白核小球藻的安全浓度分别为0.94、6.49和2.53 mg/L.结果还表明,这3种苯丙醇类抗生素,以氟苯尼考对蛋白核小球藻生长的抑制作用最大,氯霉素次之,甲砜霉素最小.The growth inhibition effects of phenicol antibiotics, including florfenicol （FF）, thiamphenicol （TAP） and chloramphenicol （CAP）, on a freshwater green algae Chlorella pyenoidosa, were examined in an artificial-lighting incubator. The results showed that FF, TAP and CAP inhibited the growth of the algae in a time-and dose-dependent manner. The medial effective concentrations （ EC50 ） of FF, TAP, and CAP for48 h were 10.42, 84.35 and 28.66 mg/L, as well as 9.40, 64.92 and 25.26 mg/L for 96 h, respectively. Therefore, the safe concentrations of FF, TAP and CAP for Chlorella pyenoidosa were O. 94, 6.49 and 2.53 mg/L respectively. Our results also demonstrated that, the three phenicol antibiotics inhibited the growth of Chlorella pyenoidosa in the order of FF 〉 CAP 〉 TAP.

关 键 词：蛋白核小球藻 氟苯尼考 甲砜霉素 氯霉素 

分 类 号：Q948[生物学—植物学]