牛病毒性腹泻BVDV2/JZ05-1基础毒株的安全性和免疫原性研究  

Safety and Immunogenicity Study of Bovine Viral Diarrhea Virus 2 Strain JZ05-1

作　　者：李海涛[1] 苗利光[1] 刘艳环[1] 朱言柱[1] 王松[1] 王文昊[1] 安亚雄[1] 

机构地区：[1]中国农业科学院特产研究所,吉林吉林132109

出　　处：《特产研究》2012年第2期5-8,共4页Special Wild Economic Animal and Plant Research

基　　金：吉林省科技发展计划(20100219)

摘　　要：本试验用已分离到的牛病毒性腹泻病毒BVDV2/JZ05-1基础毒株对犊牛免疫的安全性和免疫原性进行了研究。通过对基础毒种单剂量、超剂量、单剂量重复安全试验和免疫原性试验研究证实,BVDV2/JZ05-1对犊牛免疫是安全的,对犊牛感染BVDV有很好的免疫保护效果。The bovine viral diarrhea virus 2 strain JZ05-1 （BVDV2/JZ05-1） was isolated in this experiment. Single dose, overdose and single dose reduplication safety experiment and immunogenicity experiment were carried out in this experiment. When the calves were immunized with BVDV2/JZ05-1, the safety and immunogenicity of BVDV2/JZ05-1 were examined. The results suggested that the immunization of BVDV2/JZ05-1 is safe for calves, and it can well protect calves from the BVDV.

关 键 词：牛病毒性腹泻 安全性试验 免疫原性试验 

分 类 号：S858.235.3[农业科学—临床兽医学]