肠内营养在预防颅脑创伤患者并发多器官功能衰竭中的作用  

Effects of early enteral nutrition to prevent multiple organ failure after traumatic brain injury

作　　者：张群峰[1] 吴昆鹏[1] 肖宏[1] 桂培根[1] 

机构地区：[1]南华大学附属第二医院ICU,421001

出　　处：《中国现代药物应用》2012年第12期11-12,共2页Chinese Journal of Modern Drug Application

摘　　要：目的研究早期肠内营养对预防重型外伤性脑损伤(TBI)患者并发多器官功能衰竭中的作用。方法 GCS评分3～10分TBI患者58人,随机分为两组,观察组采用全肠内营养(TEN)支持;对照组采用全肠外营养(TPN)支持。结果 2周内观察组较对照组发生感染和多器官功能障碍病例数明显减少(P<0.01)。结论肠内营养在预防TBI患者并发感染及多器官功能衰竭中作用显著,是此类患者优先的营养途径。Objective To study the effects of early enteral nutrition on preventing multiple organ fail- ure after traumatic brain injury. Methods A total of 58 TBI patients in ICU（ GCS score 3-10）. Patients were randomized to receive either an early enteral nutrition （study group, n = 32 ）or the total parenteral nutrition （con- trol group, n =26） for at least 10 days （range, 5 - 14 days）. Results The infection and MOF rate was higher in control group compared with the study group （P 〈 0.01 ）. Conclusion Early enteral nutrition have signifi- cant effect to prevent multiple organ failure after traumatic brain injury, so it＇ s preferred nutrition route for these patients.

关 键 词：颅脑外伤 肠内营养 感染 多器官功能衰竭 

分 类 号：R651.1[医药卫生—外科学] R459.7[医药卫生—临床医学]