Nested case-control analysis with general additive-multiplicative hazard models  

作　　者：ZHENG Ming LIN Ren-xin SUN Yi YU Wen 

机构地区：[1]Department of Statistics,School of Management,Fudan University,Shanghai 200433,China

出　　处：《Applied Mathematics(A Journal of Chinese Universities)》2012年第2期159-168,共10页高校应用数学学报（英文版）（B辑）

基　　金：Supported by the National Natural Science Foundation of China(10971033,11101091)

摘　　要：This paper discusses the nested case-control analysis under a class of general additive-multiplicative hazard models which includes the Cox model and the additive hazard model as special cases.A pseudo-score is constructed to estimate the regression parameters.The resulting estimator is shown to be consistent and asymptotically normally distributed.The limiting variance-covariance matrix can be consistently estimated by the nested case-control data.A simulation study is conducted to assess the finite sample performance of the proposed estimator and a real example is provided for illustration.This paper discusses the nested case-control analysis under a class of general additive-multiplicative hazard models which includes the Cox model and the additive hazard model as special cases.A pseudo-score is constructed to estimate the regression parameters.The resulting estimator is shown to be consistent and asymptotically normally distributed.The limiting variance-covariance matrix can be consistently estimated by the nested case-control data.A simulation study is conducted to assess the finite sample performance of the proposed estimator and a real example is provided for illustration.

关 键 词：additive-multiplicative hazard nested case-control design pseudo-score survival analysis. 

分 类 号：O211.67[理学—概率论与数理统计] S816.7[理学—数学]