Fabrication and characterization of electrospun biocompatible PU/PEGMA hybrid nanofibers by in-situ UV photopolymerization  

作　　者：WANG HeYun FENG YaKai YUAN WenJie ZHAO HaiYang FANG ZiChen KHAN Musammir GUO JinTang 

机构地区：[1]School of Chemical Engineering and Technology,Tianjin University,Tianjin 300072,China [2]School of Chemistry and Chemical Engineering,Shihezi University,Shihezi 832003,China [3]Key Laboratory of Systems Bioengineering,Ministry of Education,Tianjin University,Tianjin 300072,China

出　　处：《Science China(Physics,Mechanics & Astronomy)》2012年第7期1189-1193,共5页中国科学：物理学、力学、天文学（英文版）

基　　金：financially supported by the Program for New Century Excellent Talents in University "NCET";Ministry of Education of China;the International Cooperation from Ministry of Science and Technology of China (Grant No. 2008DFA51170)

摘　　要：Poly（ethylene glycol） methacrylate （PEGMA） was introduced into a polyurethane （PU） solution in order to prepare hemocom- patible electrospun membranes for potential application as small diameter vascular scaffolds. Crosslinked PU/PEGMA hybrid nanofibers were fabricated by a reactive electrospinning process with N,N＇-methylenebisacrylamide （MBAm） as erosslinker and benzophenone （BP） as photoinitiator. The photoinduced polymerization and crosslinking reaction took place simultane- ously during the electrospinning process. No significant difference in the membrane morphology was found by SEM when PEGMA content was less than 20 wt%. The crosslinked fibrous membranes of PU/PEGMA exhibit higher hydro- philicity and mechanical strength than PU membrane. These nanofibrous membranes are potential substitutes for artificial vascular scaffolds.Poly(ethylene glycol) methacrylate (PEGMA) was introduced into a polyurethane (PU) solution in order to prepare hemocompatible electrospun membranes for potential application as small diameter vascular scaffolds. Crosslinked PU/PEGMA hybrid nanofibers were fabricated by a reactive electrospinning process with N,N′-methylenebisacrylamide (MBAm) as crosslinker and benzophenone (BP) as photoinitiator. The photoinduced polymerization and crosslinking reaction took place simultaneously during the electrospinning process. No significant difference in the membrane morphology was found by SEM when PEGMA content was less than 20 wt%. The crosslinked fibrous membranes of PU/PEGMA exhibit higher hydrophilicity and mechanical strength than PU membrane. These nanofibrous membranes are potential substitutes for artificial vascular scaffolds.

关 键 词：electrospinning CROSSLINK PHOTOPOLYMERIZATION polyurethane poly（ethylene glycol） methacrylate. 

分 类 号：TQ342.206[化学工程—化纤工业] TQ174.75