不同出生体重婴儿0～6月体重生长的前瞻性研究  

Prospective longitudinal study on the weight growth of infants with different birth weight aged 0-6 months

作　　者：张站站[1] 程茜[1] 赵勇[2] 薛海莉[2] 且亚玲[2] 

机构地区：[1]重庆医科大学附属儿童医院儿保科,重庆400014 [2]重庆医科大学公共卫生与管理学院营养与食品卫生学教研室,重庆400016

出　　处：《重庆医科大学学报》2012年第6期544-547,共4页Journal of Chongqing Medical University

基　　金：国家自然科学基金资助项目(编号:30901189)

摘　　要：目的:比较0～6月龄不同出生体重(Birth weight,BW)婴儿体重的生长情况,为不同BW婴儿早期的临床保健指导提供参考依据。方法:2010年5月至2011年9月,在重庆医科大学附属儿童医院儿保科建立前瞻性队列,分为巨大儿组、正常BW儿(Normal birth weight,NBW)组和早产低BW儿(Preterm low birth weight,PLBW)组。比较不同BW婴儿6月龄时年龄的体重Z值(Weight for age Z-score,WAZ)、超重发生率及0～6月龄体重的生长速度(ΔWAZ)。结果:(1)PLBW组86例,NBW组154例,巨大儿组107例。(2)6月龄时PLBW组、NBW组和巨大儿组WAZ均值分别是-0.60±1.12、0.46±0.83和1.17±0.92,P<0.000 1。(3)0～6月龄PLBW组、NBW组和巨大儿组ΔWAZ均值分别是2.41±1.01、0.48±0.83和-0.56±0.95,P<0.000 1。(4)PLBW组、NBW组及巨大儿组3组超重的发生率分别是4.65%、6.49%和19.63%。(5)早产儿配方奶喂养者和足月儿配方奶喂养者ΔWAZ的均值明显大于母乳喂养者,P=0.008 5;NBW组和巨大儿组中,足月儿配方奶喂养ΔWAZ的均值高于母乳喂养者,但无明显统计学差异。结论:(1)生后6个月巨大儿体重持续高水平生长,超重发生率亦高,而生长速度较NBW及PLBW慢;(2)母乳喂养的巨大儿、NBW和PLBW生后6月内体重的生长速度较配方奶喂养者慢,超重的发生率较配方奶喂养者低。Objective：To compare the weight growth of infants with different birth weight aged 0-6 months and to provide references for their clinical health care at early stage.Methods：Prospective cohort was established in the department of child health care in children＇s hospital affiliated to Chongqing medical university from May 2010 to September 2011.The cohort was divided into the macrosomia group,the normal birth weight（NBW） group and the preterm low birth weight（PLBW） group.Infants with different birth weight were compared in terms of weight for age Z-score（WAZ）,the incidence of overweight at 6th month and the weight growth speed from 0 to 6 months（ΔWAZ）.Results：（1）Respectively,86,154 and 107 examples were included in PLBW group,NBW group and macrosomia group.（2）At 6th month,the mean WAZs in PLBW group,NBW group and macrosomia group were（-0.60±1.12）,（0.46±0.83） and（1.17±0.92）,P0.000 1.（3）The mean ΔWAZs in PLBW group,NBW group and macrosomia group from 0 to 6 months were（2.41±1.01）,（0.48±0.83） and（-0.56±0.95）,P0.000 1.（4）The incidences of overweight in PLBW group,NBW group and macrosomia group at 6th month were 4.65%,6.49% and 19.63%.（5）In PLBW group,the mean ΔWAZ of preterm formula-fed infants and full term formula-fed infants was obviously higher than that of breast-fed infants,P=0.008 5;in NBW group and macrosomia group,the mean ΔWAZ of full term formula-fed was higher than that of breast-fed infants,but the differences were not significant.Conclusion：（1）A high weight growth level is maintained in macrosomia group and the incidence of overweight is the highest among three groups.The weight growth velocity is the lowest in macrosomia group compared with that of PLBW group and NBW group;（2）During the first 6 months of life,the weight growth velocity and overweight incidence are lower in breast-fed infants than in fomula-fed infants among the three groups.

关 键 词：不同出生体重儿 体重 生长 喂养方式 

分 类 号：R174.2[医药卫生—妇幼卫生保健]