苯丙胺类毒品及其衍生物的气相色谱-红外光谱分析  

Identification of Amphetamine-type Stimulants Using Gas Chromatography Coupled with Fourier Transform Infrared Spectroscopy

作　　者：张润生 王跨陡 龚飞君 叶海英 张玉荣 严松茂 杜一平[2] 张维冰[2] 

机构地区：[1]上海市毒品检验中心,上海市现场物证重点实验室一省部共建国家重点实验室培育基地,上海200083 [2]上海市功能性材料化学重点实验室,华东理工大学,上海200237

出　　处：《分析化学》2012年第6期915-919,共5页Chinese Journal of Analytical Chemistry

基　　金：国家自然科学基金(No.20975039);上海市公安局科技项目基金(No.2006002)资助

摘　　要：采用气相色谱-傅立叶变换红外光谱联用技术,建立了9种苯丙胺类毒品及其衍生物的分析鉴别方法。采用HP-1(30 m×0.32 mm,0.25μm)毛细管柱,MCT红外检测器与氢火焰检测器同时检测,在程序升温条件下,以十七烷为内标物,研究已知对照品的色谱保留行为及其气态红外光谱图特征,建立相应的特征吸收峰数据库,作为鉴别分析的依据。色谱保留时间与红外特征吸收峰联合鉴别法极大地提高了鉴别的准确性。将发展的方法应用于可疑毒品物证中苯丙胺类及其衍生物毒品样品的鉴别,获得了理想的结果。本方法可用于涉毒案件毒品物证的检验,特别适用于混合毒品成分的检验。Gas chromatography-infrared spectroscopy technique has been used for the quantitative analysis of amphetamine-type stimulants.Capillary column of HP-1（30 m×0.32 mm,0.25 μm） was coupled with MCT infrared spectroscopy and flame ionization detecters using temperature programming for identification of nine ampletamine-type stimulants.Chromatographic retention behaviors were studied using heptadecane as internal standard for separation and identification of the stimulants.On another hand,infrared spectra of the gaseous amphetamine-type stimulants were measured using chemical reference substances of the stimulants and the characteristic peaks from the collected spectra were supplied as an assistant identification.The cooperation of information from retention time and infrared spectrum should improve the reliability of the method.The analysis of real samples showed satisfactory results.The method could be applied to the stimulant identification,especially to that of complicated sample.

关 键 词：毒品鉴定 苯丙胺 红外光谱 气相色谱 

分 类 号：R114[医药卫生—卫生毒理学] O657.33[医药卫生—公共卫生与预防医学]