孟鲁司特治疗慢性阻塞性肺疾病急性加重期80例疗效分析  

Efficacy of montelukast on 80 patients with acute exacerbations of chronic obstructive pulmonary disease

作　　者：雷震[1] 左莹[1] 

机构地区：[1]川北医学院附属医院内科,四川南充637000

出　　处：《实用药物与临床》2012年第6期342-343,共2页Practical Pharmacy and Clinical Remedies

摘　　要：目的观察孟鲁司特治疗慢性阻塞性肺疾病急性加重期的疗效。方法 80例患者随机分为治疗组和对照组。对照组采用常规治疗,治疗组在此基础上加用孟鲁司特片,疗程为2周。分别比较两组治疗前及治疗后第14天的血气分析和吸入支气管扩张剂后肺功能测定相关指标。结果治疗后治疗组肺功能各项指标优于对照组,差异有统计学意义(P<0.05);两组血气分析差异无统计学意义(P>0.05)。结论孟鲁司特可改善慢性阻塞性肺疾病急性加重期患者的肺功能。Objective To explore the curative effect of montelukast on 80 patients with acute exacerbations of chronic obstructive pulmonary disease.Methods 80 patients were randomly divided into control group and treatment group.Patients of the two groups received conventional treatment for two weeks,while treatment group were added montelukast.Blood gas analysis and pulmonary function test were checked up before treatment and after 14 days.Results After the treatment,the pulmonary function of the treatment group was better than that of control group（P0.05）;But the blood gas analysis showed no significant difference compared with control group（P0.05）.Conclusion Montelukast can improve the pulmonary function in patients with acute exacerbations of chronic obstructive pulmonary disease.

关 键 词：孟鲁司特 慢性阻塞性肺疾病急性加重期 血气分析 肺功能 

分 类 号：R563.9[医药卫生—呼吸系统]