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出 处:《医学临床研究》2012年第5期835-837,共3页Journal of Clinical Research
基 金:湖南省科技厅项目(项目编辑:2009FJ3185)
摘 要:[目的]探讨抑制素A、激活素A在预测先兆流产妊娠结局中的作用.[方法]选择妊娠6~11周的孕妇1000例,随访至孕13周,选择其中先兆流产发展为难免流产者40例(A组),出现先兆流产但经过干预后继续妊娠者75例(B组),正常妊娠者681例(C组),采用ELISA法检测并比较三组孕妇血清抑制素A与激活素A的浓度.[结果]A组孕妇抑制素A及激活素A浓度显著低于B族和C组,差异有显著性(P〈0.01);B组孕妇抑制素A及激活素A浓度稍低于C组,但差异无显著性(P〉0.05).[结论]抑制素A与激活素A可以作为预测先兆流产妊娠结局的良好标记物.[Objective]To explore the role of inhibin A and activin A in the prediction of the pregnancy outcome of threatened abortion. [Methods] Totally 1000 pregnant women with 6-10 weeks of pregnancy were selected and followed up to 13 weeks after pregnancy. Group A were 40 pregnant women with inevitable abor-tion developed from threatened abortion. Group B were 75 continuous pregnant women after intervention of threatened abortion. Group C were 681 normal pregnant women. Serum inhibin A and activin A of pregnant women among three groups were detected by ELISA and compared. [Results] Serum inhibin A and aetivin A in group A were markedly lower than those in group B and group C, and there were significant differences( P〈0.01). Serum inhibin A and activin A in group t3 were slightly lower than those in group C, and there were significant differences( P〉0.05). [Conclusion]Inhibin A and aetivin A can be used as good markers for pre-dicting the pregnancy outcome of threatened abortion.
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