右旋美托咪啶和布比卡因混合液用于臂丛神经阻滞的临床研究  

Clinical Research of Dexmedetomidine with Bupivacaine Applied on Brachial Plexus Block

作　　者：申佳凡[1] 王嘉争[1] 王德明[1] 肖继[1] 

机构地区：[1]南华大学附属第二医院麻醉科,湖南衡阳421001

出　　处：《医学综述》2012年第11期1751-1752,共2页Medical Recapitulate

摘　　要：目的评价右旋美托咪啶加入布比卡因对肌间沟法臂丛神经阻滞的影响。方法选择63例ASAⅠ～Ⅱ级拟行上臂或手部行手术的患者,随机分成两组:布比卡因组(B组)与布比卡因和右旋美托咪啶混合液组(BD组),B组32例,BD组31例。使用神经刺激仪引导行肌间沟法臂丛神经阻滞,B组给予0.25%布比卡因25 mL,BD组给予含有1μg/kg右旋美托咪啶的0.25%布比卡因混合液25 mL。记录两组患者的心率(HR)、平均动脉压(MAP)、血氧饱和度(SpO2)以及运动和感觉的阻滞时间。结果两组患者的HR、MAP和SpO2比较差异无统计学意义(P>0.05);两组患者的运动和感觉的阻滞时间比较差异有统计学意义(P<0.05)。结论右旋美托咪啶加入布比卡因用于肌间沟法臂丛神经阻滞可以延长感觉和运动的阻滞时间,对血流动力学无明显影响。Objective To investigate the clinical influence of dexmedetomidine plus bupivacaine on brachial plexus block.Methods 63 cases of ASA class Ⅰ to Ⅱ patients scheduled for upper extremity operation were randomly divided into group bupivacaine（group B）and group dexmedetomidine（group BD）,group B（n=32）were treated with 0.25% bupivacaine 25 mL,group BD（n=31）were treated with 0.25% bupivacaine plus 1 μg/kg dexmedetomidine 25 mL.HR,MAP,SpO2,the duration of sensory block and the retention of motor block were recorded.Results There was no significant difference in HR,MAP,and SpO2（P〉0.05）.Compared with group B,the duration of sensory block and the retention of motor block were longer in group BD（P〈0.05）.Conclusion Dexmedetomidine as an adjuvant treatment for brachial plexus block with bupivacaine can prolong the duration of sensory block and the retention of motor block,and no obvious effect on hemodynamic.

关 键 词：右旋美托咪啶 臂丛神经阻滞 布比卡因 

分 类 号：R614[医药卫生—麻醉学]