经尿道前列腺等离子剜除术治疗前列腺增生  

Treatment of benign prostatic hyperplasia with transurethral plasma kinetic enucleation of prostate

作　　者：孟庆超[1] 李明峰[1] 仇让学[1] 张磊[1] 郑龙宝[1] 

机构地区：[1]解放军第92医院泌尿外科,福建南平353000

出　　处：《军医进修学院学报》2012年第7期719-721,共3页Academic Journal of Pla Postgraduate Medical School

摘　　要：目的对比白细胞介素6(interleukin-6,IL-6)和C反应蛋白(C reactive protein,CRP)在不同术式前后的变化,进而评价经尿道前列腺等离子剜除术(transurethral plasma kinetic enucleation of prostate,TUPKEP)治疗前列腺增生(benign prostatic hyperplasia,BPH)的可行性。方法 64例良性前列腺增生患者分别行经尿道前列腺汽化电切术(transurethral vapor-resection of the prostate,TUVP组)16例、经尿道前列腺等离子剜除术(TUPKEP组)48例,尿道前列腺等离子剜除术采用英国Gyrus-PKS系统。采用酶联免疫吸附法测定IL-6和CRP在两组患者手术前2h、术后24h、48h血清中的水平。结果 1)血清IL-6水平术前两组无统计学差异(P>0.05),术后均明显高于术前(P<0.05);术后24h TUVP组(3.86±1.42)μg/L、TUPKEP组(2.27±1.15)μg/L(P<0.05);48h TUVP组(1.07±1.03)μg/L、TUPKEP组(0.81±1.24)(P<0.05)。2)血清CRP水平术前两组无统计学差异(P>0.05),术后均明显高于术前(P<0.05);术后24h TUVP组(41.54±12.88)mg/L、TUPKEP组(30.29±10.14)mg/L(P<0.05),48h TUVP组(72.57±16.85)mg/L、TUPKEP组(58.29±11.56)(P<0.05)。结论相对于TUVP,TUPKEP创伤较小,更适合应用于治疗良性前列腺增生。Objective To assess the feasibility of transurethral plasma kinetic enucleation of prostate（TUPKEP） for benign prostatic hyperplasia（BPH） by comparing changes in interleukin-6（IL-6） and C reactive protein（CRP） before and after different surgical procedures. Methods Sixty-four patients with BPH were included in this study. Of these patients, 16 who underwent transurethral vapor-resection of the prostate（TUVP） served as TUVP group and 48 who underwent TUPKEP with the British Gyrus-PKS system served as TUPKEE Their serum IL-6 and CRP levels were measured 2h before operation and 24 and 48h after operation by ELISA. Results No significant difference was found in serum IL-6 level between the two groups before operation（P〉0.05） . However, the serum IL-6 level was significantly higher in the patients after operation than before operation（P〈0.05）. The serum IL-6 level was significantly higher in TUVP group than in TUPKEP group 24 and 48h after operation（（3.86 ± 1.42） μ g/L vs （2.27 ± 1.15） μg/L, （1.07 -1.03）μ g/L vs （0.81 ± 1.24）μ g/L, P〈0.05）. No significant difference was found in serum CRP level in the patients before operation（P〉0.05）. However, the serum CRP level was significantly higher in the patients after operation than before operation（P〈0.05）. The serum CRP level was significantly higher in the TUVP group than in the TUPKEP group 24 and 48 h after operation（（41.54 ± 12.88）mg/L vs （30.29 ± 10.14）mg/L, （72.57 ± 16.85）mg/L vs （58.29 ± 11.56）mg/L, P〈0.05）. Conclusion TUPKEP is more suitable than TUVP to BPH with less damages.

关 键 词：经尿道前列腺等离子剜除术 前列腺增生 白细胞介素-6 C反应蛋白质 

分 类 号：R697.32[医药卫生—泌尿科学]