白芍总苷联合小剂量雷公藤多甙治疗寻常型银屑病临床观察  

Effect of combined total glucoside from while peony and small dose of poly-glycoside from Tripterygium wilfordii Hook.f on common psoriasis

作　　者：胡银娥[1] 王斌[1] 瞿伟[1] 高俊玲[1] 代淑芳[1] 

机构地区：[1]河南大学淮河医院皮肤科,河南开封475000

出　　处：《军医进修学院学报》2012年第7期733-735,共3页Academic Journal of Pla Postgraduate Medical School

摘　　要：目的观察白芍总苷胶囊联合小剂量雷公藤多甙治疗寻常型银屑病90例临床疗效。方法将寻常型银屑病患者180例随机分为治疗组、对照组各90例;治疗组口服白芍总苷胶囊和小剂量雷公藤多甙片,对照组口服小剂量雷公藤多甙片。疗程均为3个月。治疗前、后检查2组患者的血、尿常规及肝、肾功能,同时观察患者的不良反应。结果治疗组有效率84.4%,对照组有效率64.4%,两组比较差异有统计学意义(P<0.01)。结论白芍总苷胶囊联合小剂量雷公藤多甙治疗寻常型银屑病疗效满意,值得临床应用。Objective To observe the clinical effect of combined total glucoside from peony（TGP） and small dose of poly-glycoside from Tripterygium wilfordii Hook.f in 90 patients with common psoriasis. Methods One hundred and eighty patients with common psoriasis were randomly divided into treatment group（n=90） and control group（n=90）. Patients in treatment group received TGP and tablets of poly-glycoside from Tripterygium wilfordii Hook.f at a small dose and those in control group only administered tablets of poly-glycoside from Tripterygium wilfordii Hook.f at a small dose for 3 months. Then, routine blood and urine examinations were performed to detect their liver and kidney functions before and after treatment, and their adverse reactions were observed. Results The effective rate was 84.4% and 64.4% respectively for the treatment group and control group（P〈0.01）. Conclusion Combined TGP and small dose of poly-glycoside from Tripterygium wilfordii Hook.f can achieve satisfactory therapeutic effects on common psoriasis, and is thus worthy to be applied in treatment of common psoriasis.

关 键 词：白芍总苷 雷公藤多甙 寻常型银屑病 疗效观察 

分 类 号：R751.05[医药卫生—皮肤病学与性病学]