左旋龙脑对小鼠耐缺氧的影响  

Effect of borneol on anoxia-tolerance in mice

作　　者：姜成[1] 杨贵[1] 

机构地区：[1]武警四川总队医院药剂科,四川乐山614000

出　　处：《四川生理科学杂志》2012年第2期63-65,共3页Sichuan Journal of Physiological Sciences

摘　　要：目的:研究左旋龙脑对小鼠的耐缺氧作用。方法:采用常压耐缺氧、断头张口呼吸、NaNO2中毒缺氧、氰化钾中毒缺氧、氯化镁所致心脏骤停缺氧等方法观察左旋龙脑抗缺氧作用。结果:除NaNO2中毒缺氧模型外,左旋龙脑对其余各种方法所致的缺氧模型均有显著的延长死亡时间作用。结论:左旋龙脑有显著的抗小鼠心肌、脑缺血缺氧作用。Objective： To study the effect of borneol on anoxia-tolerance in mice. Methods： The effect of bomeol on anoxia-tolerance in mice was observed by methods of hypoxia under normal pressure, decollation mouth breathing, NaNCO2 induced hypoxia, KCN induced hypoxia and heart arrest induced hypoxia by MgCl2. Results： Borneol could prolong the survival time in all anoxic mice models, except NaNO2 inducedhypoxia mice model. Conclusion： Borneol has the effect of antianoxia on mice.

关 键 词：左旋龙脑 耐缺氧 

分 类 号：R285.5[医药卫生—中药学]