同一仪器不同试剂测定纤维蛋白原的方法评价  

Evaluation of fibrinogen determination method with different reagents in same equipment

作　　者：郭桂英[1] 郭勇[1] 佘仕金 郑春莲[1] 

机构地区：[1]四川省乐山市人民医院检验科,614000

出　　处：《检验医学与临床》2012年第12期1438-1439,共2页Laboratory Medicine and Clinic

摘　　要：目的对用配套进口试剂和国产试剂在CA-1500型全自动血凝仪上测定纤维蛋白原(Fib)的两种方法进行评价。方法用正常和异常值临床样本检测Fib,并对测定结果进行统计学分析。结果 CA-1500型全自动血凝仪Von Clauss法和凝血酶原导出法(PT-der)测定Fib,当Fib含量低于5g/L时,测定结果差异无统计学意义;当Fib含量大于5g/L时,后者测定的Fib结果偏高。结论建议临床在应用全自动血凝仪时,当PT-der衍算出来的Fib较高时,应改用Von Clauss法进行测定。Objective To evaluate the two methods of fibrinogen（Fib） determination with matched imported reagent and domestic reagent in the CA-1500 fully automatic coagulation analyzer. Methods The clinical specimens with normal and abnormal values were adopted to detect plasma Fib and the detection results were statistically ana- lyzed. Results In Fib detection with Von Clauss method and PT-der method in CA 1500 fully automatic coagulation analyzer, when Fib level 〈 5g/L, the detection results had no statistical difference, when Fib level 〉5 g/L, the detec- tion results of the PT-der method was on the high side. Conclusion It is suggested that when Fib value calculated by the PT-der method in the fully automatic coagulation analyzer is higher in clinic,the Fib detection should be changed to adopt Von Clauss method.

关 键 词：全自动血凝仪 纤维蛋白原 凝血酶原导出法 Von CLAUSS法 

分 类 号：R446.11[医药卫生—诊断学]