广州汉族人群DYS19、DYS389Ⅰ/Ⅱ、DYS390多态性及其单体型  

Y-DNA STRs Polymorphisms and Haplotypes in Guangzhou Han Population

作　　者：唐双柏[1] 郭景元[1] 刘超[2] 梁赏猷[2] 王穗保[2] 

机构地区：[1]中山医科大学法医系,广东广州510089 [2]广州市公安局刑事科学技术研究所,广东广州510030

出　　处：《遗传》2000年第1期11-14,共4页Hereditas（Beijing)

摘　　要：用PCR结合PAGE技术观察111例广州汉族男性DYS19、DYS389Ⅰ/Ⅱ、DYS390等位基因及单体型分布状况。结果显示 :广州地区汉族男性DYS19基因座观察到5种等位基因 ,DYS389Ⅰ观察到4种等位基因 ,DYS389Ⅱ观察到5种等位基因 ,DYS390观察到5种等位基因 ;χ2 检验表明上述各等位基因频率分布与其他地区人群存在明显的差异。此外 ,还观察到72种由上述基因座共同构成的单体型 ,单体型多样性达0 953。In order to apply a set of useful and high polymorphic Y STRs in forensic practice and genetic analysis,we performed a population genetic study from Chinese.The allele distributions of the systems DYS19、DYS389Ⅰ/Ⅱ、 and DYS390 were investigated in sample of 111 unrelated males from the area of Guangzhou, China.PCR products were detected using polyacrylamide gel electrophoresis and silver staining.5、4、5、5 alleles were observed in locus DYS19、DYS389Ⅰ、DYS389Ⅱ、DYS390 respectively.Different allele frequency distributions were observed when compared to other population.Haplotype frequency date of 72 different types were obtained.

关 键 词：Y染色体 短串联重复序列 遗传多态性 汉族 

分 类 号：Q987[生物学—遗传学]