献血人群红细胞血型意外抗体的筛选  

Screening unexpected antibody of red cells blood group in the blood donors

作　　者：祝宏[1,2] 洪小珍[1,2] 吴亚玲[1,2] 励晓涛[1,2] 马开荣[1,2] 兰小飞[1,2] 朱发明[1,2] 

机构地区：[1]浙江省血液中心,杭州310006 [2]卫生部血液安全研究重点实验室,杭州310006

出　　处：《中国卫生检验杂志》2012年第6期1339-1340,1343,共3页Chinese Journal of Health Laboratory Technology

基　　金：浙江省自然科学研究基金(Y2101289);浙江省医药卫生科研基金(2011RCB012)

摘　　要：目的:分析献血人群中红细胞血型意外抗体的情况,并对抗体特性进行确认。方法:应用O型红细胞结合PK7200血型检测系统筛选红细胞血型意外抗体,利用谱细胞鉴定抗体特性。结果:在献血人群中红细胞血型意外抗体阳性率为0.025%,意外抗体以抗M和冷凝集素为主。发现两例类孟买型血型和两例p血型。结论:献血人群中存在低比例的红细胞血型意外抗体,在献血者血型检测中应加以重视。Objective：To determine unexpected antibody of red cells blood group in the blood donors and identify the characteristics of the antibody.Methods：The unexpected antibody was screened by O blood group cells and PK7200 system.Characteristics of the antibody were identified by panel cells..Results：The prevalence rate of unexpected antibody was 0.025% in the blood donors.The common unexpected antibodies were anti-M and cold agglutinin.Two cases with para-Bombay phenotype and two cases with p phenotype were found.Conclusion：Low prevalence of unexpected antibody existed in the blood donors.It is important to screen unexpected antibody in donor＇s blood grouping.

关 键 词：献血者 意外抗体 

分 类 号：R193.3[医药卫生—卫生事业管理]