藤黄属植物的化学成分和药理作用研究进展  

Advances in studies on chemical constituents of plants in Garcinia L.and their pharmacological activities

作　　者：张俊艳[1,2] 韩英梅[1] 常允平[1,2] 

机构地区：[1]天津药物研究院天津市新药设计与发现重点实验室,天津300193 [2]天津中医药大学,天津300193

出　　处：《现代药物与临床》2012年第3期297-303,共7页Drugs & Clinic

基　　金：国家重大新药创制专项(2011ZX09401-009)

摘　　要：藤黄属植物在东南亚地区广泛分布,其中一些植物作为民间药物有着悠久的用药历史。该属植物普遍具有抗肿瘤、抗炎、抗菌等药理作用,而且已有呫吨酮、双黄酮、苯甲酮、萜类等多种结构类型的化学成分从该属植物中分离得到.概述了近十年来从藤黄属植物中分离得到的新化合物和首次发现的天然产物及其化学成分的药理活性研究进展,为该属植物的深入研究提供依据。The plants in Garcinia L.are widely distributed in Southeast Asia and some of them have been used as folk medicine for a long time.The plants from this genera often have antitumor,anti-inflammation,and antibacterial pharmacological activities and chemical constituents,such as xanthones,biflavones,benzophenones,and terpenoids have been isolated from this genera.This paper summarizes these new compounds and natural products firstly isolated from the plants in Garcinia L.and the research progress on their pharmacological activities during last decade,so as to provide the basic evidences for further investigation of the plants in Garcinia L.

关 键 词：藤黄属 化学成分 抗肿瘤 抗HIV 抗炎 

分 类 号：R282.71[医药卫生—中药学] R285.6[医药卫生—中医学]