不同血液净化方式对高脂血症性胰腺炎的作用  

Effects of different blood purification modes on hyperlipidemic pancreatitis

作　　者：常为民[1] 杨进军[1] 

机构地区：[1]重庆市第九人民医院ICU,400700

出　　处：《重庆医学》2012年第17期1706-1707,共2页Chongqing medicine

摘　　要：目的探讨不同血液净化方式对高脂血症性胰腺炎的治疗作用。方法选取该院2005～2010年收治的26例高脂血症性胰腺炎患者,分为HP+CVVH组(16例)及CVVH组(10例),比较治疗前、后三酰甘油、肿瘤坏死因子-α(TNF-α)、A-PACHEⅡ评分、临床症状及存活率等的变化。结果两组患者治疗后,临床症状缓解,三酰甘油、TNF-α及APACHEⅡ评分均降低,但HP+CVVH治疗组患者血清血脂、细胞因子及APACHEⅡ评分在相同时间点明显低于CVVH组(P<0.05),存活率也明显高于CVVH组。结论 HP+CVVH比CVVH能更有效地清除三酰甘油及炎症因子,提高生存率。Objective To evaluate the curative effect of different blood purification modes on hyperlipidemic pancreatitis. Methods 26 patients with hyperlipidemie pancreatitis treated in our hospital from 2005 to 2010 were divided to HP＋CVVH group（n-16） and CVVH group（n= 10）. Blood triglyceride level, tumor necrosis factor-a（TNF-a）,APACHE Ⅱ scores, clinical symptoms and survival rate were observed before and after treatment. Results The clinical symptoms after treatment in the two groups were improved,and the level of triglyceride,TNF-a and the APACHE Ⅱ scores all were reduced. However, triglyceride, TNF-a and APACHE lI scores in the HP＋CVVH group were lower than those in the CVVH group at the same time points,showing statistical difference（P〈0.05）, the survival rate was obviously higher than that in the CVVH group . Conclusion HP＋CVVH is more effective in eliminating triglyceride and inflammatory factors and increases the survival rate.

关 键 词：HP+CVVH CVVH 高脂血症性胰腺炎 

分 类 号：R589.2[医药卫生—内分泌] R576[医药卫生—内科学]