医院就诊人群宫颈病变机会性筛查资料分析  

Data analysis on opportunistic screening for cervical lesions in outpatients

作　　者：高娜[1] 吴涛[2] 石红[1] 郑军[1] 陆晓云[1] 

机构地区：[1]大连医科大学附属第一医院妇产科,辽宁大连116011 [2]大连医科大学附属第二医院肿瘤科,辽宁大连116027

出　　处：《现代医药卫生》2012年第11期1617-1618,1620,共3页Journal of Modern Medicine & Health

摘　　要：目的探讨医院就诊患者进行宫颈癌机会性筛查的价值。方法回顾性分析2007年6月至2011年5月大连医科大学附属第一医院妇产科门诊进行宫颈癌机会性筛查(opportunistic screening,OS)的资料,筛查方法包括液基细胞学、高危型人乳头瘤病毒(HPV)DNA检测以及二者联合应用;以阴道镜下宫颈活组织检查病理诊断确诊宫颈病变及宫颈癌。结果共收治门诊患者335 912例,其中接受OS 24 978例,占门诊就诊例数7.44%(24 978/335 912)。筛查方案分别为:液基细胞学17 632例(70.59%),联合应用液基细胞学和HPV DNA检测7 346例(29.41%)。最普遍采用的筛查方法是液基细胞学。检出上皮内瘤样病变(CIN)614例(2.46%),宫颈癌43例(0.17%)。结论医院内就诊人群宫颈病变检出率高,OS对防治宫颈癌具有重要意义。Objective To investigate the value of opportunistic screening（OS） for cervical cancer in outpatients. Methods The OS data from the First Affiliated Hospital of Dalian Medical University form June 2007 to May 2011 were collected and retrospectively analyzed. The screening protocols included the liquid-based cytology, high risk type human papillomavirus （HPV）- DNA test and their combination detection. All the suspected cases underwent colposcopy and biopsy. Cervical lesion or cervical cancer was confirmed pathologically. Results Among 335 912 outpatients,24 978 cases（7.44%） received OS,including 17 632 cases （70.59%） of liquid-based cytology and 7 346 cases （29.41%） of liquid-based cytology combined HPV DNA test. Liquid- based cytology was most commonly used in screening. Cervical intraepithelial neoplasia （CIN） was detected in 614 cases （2.46%） and cervical cancer in 43 cases （0.17%）. Conclusion Outpatients have the high detection rate of cervical lesions. OS plays an important significance in the diagnosis and treatment of cervical cancer.

关 键 词：普查 宫颈疾病 细胞学 人乳头瘤病毒16 人乳头瘤病毒18 

分 类 号：R711.32[医药卫生—妇产科学]